seven in absentia 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:75.90 ovary:- testis:82.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_134457
Gene ID 140593
Unigene ID Rn.29192
Probe set ID -
Ensembl ID ENSRNOG00000013703

Orthologous Gene

Human[2]  NM_005067
Mouse[2]  NM_009174

Chromosomal Region

2q31  [148,022,641  -  148,040,703]

Gene Family (Interpro ID)

IPR018121  Seven-in-absentia protein, TRAF-like domain
IPR008974  TRAF-like

Link to Pubmed  (Pubmed ID)

11786535
16394250
19224863

Gene Ontology  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0044257  cellular protein catabolic process
GO:0007275  multicellular organismal development
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0031396  regulation of protein ubiquitination
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0043025  cell soma
GO:0005829  cytosol
GO:0005769  early endosome
GO:0043005  neuron projection
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0031624  ubiquitin conjugating enzyme binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding