seven in absentia 1A

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:71.10 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:38 ovary:- testis:82.30 heart:58.20 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:177.70 thyroid/parathyroid:- adrenal gland:- pancreas:113.80 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_080905
Gene ID 140941
Unigene ID Rn.73937
Probe set ID -
Ensembl ID ENSRNOG00000015143

Orthologous Gene

Human[4]  NM_001006610, NM_003031
Mouse[4]  NM_001006610, NM_003031

Chromosomal Region

19p11  [21,738,838  -  21,740,234]

Gene Family (Interpro ID)

IPR018121  Seven-in-absentia protein, TRAF-like domain
IPR008974  TRAF-like

Link to Pubmed  (Pubmed ID)

2129524
8889548
10469171
11686852
11786535
14506261
15326124
15951807
16230351
18065497
18280659
19224863
19940145
21336655

Gene Ontology  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0030154  cell differentiation
GO:0007141  male meiosis I
GO:0007275  multicellular organismal development
GO:0051402  neuron apoptosis
GO:0043065  positive regulation of apoptosis
GO:0009791  post-embryonic development
GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0030163  protein catabolic process
GO:0031648  protein destabilization
GO:0042787  protein ubiquitination during ubiquitin-dependent protein catabolic process
GO:0040014  regulation of multicellular organism growth
GO:0007283  spermatogenesis

Cellular Component

GO:0030877  beta-catenin destruction complex
GO:0005829  cytosol
GO:0005769  early endosome
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0042803  protein homodimerization activity
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding