Interleukin 23, alpha subunit p19

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:82.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_130410
Gene ID 155140
Unigene ID Rn.81073
Probe set ID -
Ensembl ID ENSRNOG00000003254

Orthologous Gene

Human[1]  NM_016584
Mouse[1]  NM_031252

Chromosomal Region

7q11  [1,584,112  -  1,586,226]

Gene Family (Interpro ID)

IPR009079  Four-helical cytokine-like, core
IPR003573  Interleukin-6/G-CSF/MGF

Link to Pubmed  (Pubmed ID)

12417590
12477932
15489334
15990448
19714651
19935773

Gene Ontology  (GO ID)

Biological Process

GO:0050829  defense response to Gram-negative bacterium
GO:0051607  defense response to virus
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0032693  negative regulation of interleukin-10 production
GO:0042104  positive regulation of activated T cell proliferation
GO:0010535  positive regulation of activation of JAK2 kinase activity
GO:0002230  positive regulation of defense response to virus by host
GO:0032725  positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032729  positive regulation of interferon-gamma production
GO:0032733  positive regulation of interleukin-10 production
GO:0032735  positive regulation of interleukin-12 production
GO:0032740  positive regulation of interleukin-17 production
GO:0043382  positive regulation of memory T cell differentiation
GO:0032819  positive regulation of natural killer cell proliferation
GO:0090023  positive regulation of neutrophil chemotaxis
GO:0051135  positive regulation of NK T cell activation
GO:0051142  positive regulation of NK T cell proliferation
GO:0045672  positive regulation of osteoclast differentiation
GO:0001916  positive regulation of T cell mediated cytotoxicity
GO:0042102  positive regulation of T cell proliferation
GO:0002827  positive regulation of T-helper 1 type immune response
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032760  positive regulation of tumor necrosis factor production
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042520  positive regulation of tyrosine phosphorylation of Stat4 protein
GO:0042523  positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0042510  regulation of tyrosine phosphorylation of Stat1 protein
GO:0042098  T cell proliferation
GO:0048771  tissue remodeling

Cellular Component

GO:0070743  interleukin-23 complex

Molecular Function

GO:0005125  cytokine activity
GO:0045519  interleukin-23 receptor binding