caspase 12

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_130422
Gene ID 156117
Unigene ID Rn.81078
Probe set ID -
Ensembl ID ENSRNOG00000033434

Orthologous Gene

Human [0]  
Mouse[2]  NM_009808

Chromosomal Region

8q11  [2,083,906  -  2,110,511]

Gene Family (Interpro ID)

IPR001315  Caspase Recruitment
IPR017350  Caspase, interleukin-1 beta convertase
IPR011029  DEATH-like
IPR011600  Peptidase C14, caspase catalytic
IPR002398  Peptidase C14, caspase precursor p45
IPR015917  Peptidase C14, caspase precursor p45, core

Link to Pubmed  (Pubmed ID)

12031969
12598725
14675152
14732288
15113843
15556633
15843901
15855338
16092975
16139996
16236330
16574987
16847061
16955111
16979584
17083921
17433554
18273070
18280615
18316105
18332441
18456407
18477628
18603371
18675883
18787714
19215662
19301230
19339625
19406177
19594550
19769458
20444431
20871144
21429313
21476018
21525936
21784110
21845883
22099262

Gene Ontology  (GO ID)

Biological Process

GO:0007568  aging
GO:0006915  apoptosis
GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0030968  endoplasmic reticulum unfolded protein response
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0016540  protein autoprocessing
GO:0006508  proteolysis
GO:0042981  regulation of apoptosis
GO:0034059  response to anoxia
GO:0009409  response to cold
GO:0042493  response to drug
GO:0034976  response to endoplasmic reticulum stress
GO:0045471  response to ethanol
GO:0010035  response to inorganic substance
GO:0010041  response to iron(III) ion
GO:0035094  response to nicotine
GO:0010243  response to organic nitrogen
GO:0006926  virus-infected cell apoptosis

Cellular Component

GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005622  intracellular
GO:0043231  intracellular membrane-bounded organelle
GO:0005634  nucleus

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0008234  cysteine-type peptidase activity
GO:0004175  endopeptidase activity
GO:0002020  protease binding
GO:0005515  protein binding