SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:215.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:71.10 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:491.60 bone marrow:- adipose:294.40 bone:156.20 skin:235.40
GeneChip cerebrum:6.05 cerebellum:6.21 brain stem:6.13 corpus callosum/glia:- pineal gland:- peripheral nerve:5.78 spine:- retina:- eye:6.36 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.69 thymus:5.82 bone marrow:6.17 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:238.90 prostate:189.80 ovary:114.10 testis:82.30 heart:213.30 muscle:- esophagus:- stomach:1077.60 intestine:- colon:-     liver/hepato:39.90        lung:304    bladder:- kidney:63.80 pituitary:118.40 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6.04 muscle:6.25 esophagus:- stomach:- intestine:5.82 colon:5.72 liver/hepato:- lung:- bladder:- kidney:5.68 pituitary:5.89 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_134368
Gene ID 171379
Unigene ID Rn.23417
Probe set ID X99723cds_at  [RG_U34A]
Ensembl ID ENSRNOG00000009271

Orthologous Gene

Human[42]  NM_001128844, NM_001128845, NM_001128846, NM_001128847, NM_001128848, NM_001128849, NM_003072
Mouse[2]  NM_001174078, NM_001174079, NM_011417, NM_001128847, NM_001128848, NM_001128849, NM_003072

Chromosomal Region

8q13  [20,720,915  -  20,812,157]

Gene Family (Interpro ID)

IPR014001  DEAD-like helicase, N-terminal
IPR013999  HAS subgroup
IPR014021  Helicase, superfamily 1/2, ATP-binding domain
IPR014012  Helicase/SANT-associated, DNA binding
IPR006562  HSA

Link to Pubmed  (Pubmed ID)

8895581
9001244
11306337
12477932
12684665
14676303
15287030
16793760
17075831
17666433
19081374

Gene Ontology  (GO ID)

Biological Process

GO:0043044  ATP-dependent chromatin remodeling
GO:0001832  blastocyst growth
GO:0001835  blastocyst hatching
GO:0000902  cell morphogenesis
GO:0006338  chromatin remodeling
GO:0060318  definitive erythrocyte differentiation
GO:0010424  DNA methylation on cytosine within a CG sequence
GO:0035116  embryonic hindlimb morphogenesis
GO:0048562  embryonic organ morphogenesis
GO:0048730  epidermis morphogenesis
GO:0030198  extracellular matrix organization
GO:0030900  forebrain development
GO:0007403  glial cell fate determination
GO:0007507  heart development
GO:0060347  heart trabecula formation
GO:0030902  hindbrain development
GO:0043966  histone H3 acetylation
GO:0001701  in utero embryonic development
GO:0030216  keratinocyte differentiation
GO:0001889  liver development
GO:0006346  methylation-dependent chromatin silencing
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0030308  negative regulation of cell growth
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0007399  nervous system development
GO:0003407  neural retina development
GO:0022008  neurogenesis
GO:0006337  nucleosome disassembly
GO:0043923  positive regulation by host of viral transcription
GO:0043388  positive regulation of DNA binding
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006355  regulation of transcription, DNA-dependent
GO:0019827  stem cell maintenance
GO:0006351  transcription, DNA-dependent
GO:0001570  vasculogenesis

Cellular Component

GO:0000792  heterochromatin
GO:0000790  nuclear chromatin
GO:0005719  nuclear euchromatin
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005726  perichromatin fibrils
GO:0016514  SWI/SNF complex

Molecular Function

GO:0050681  androgen receptor binding
GO:0005524  ATP binding
GO:0016887  ATPase activity
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0008094  DNA-dependent ATPase activity
GO:0004386  helicase activity
GO:0070577  histone acetyl-lysine binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0047485  protein N-terminus binding
GO:0030957  Tat protein binding
GO:0003713  transcription coactivator activity
GO:0003714  transcription corepressor activity
GO:0008134  transcription factor binding