sulfatase 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:38 ovary:- testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:104.70 colon:-     liver/hepato:-        lung:202.60    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_134378
Gene ID 171396
Unigene ID Rn.161961
Probe set ID -
Ensembl ID ENSRNOG00000009037

Orthologous Gene

Human[12]  NM_001128204, NM_001128205, NM_001128206, NM_015170
Mouse[1]  NM_001198565, NM_001198566, NM_172294, NM_015170

Chromosomal Region

5q11  [5,582,896  -  5,748,106]

Gene Family (Interpro ID)

IPR017850  Alkaline-phosphatase-like, core domain
IPR000917  Sulfatase

Link to Pubmed  (Pubmed ID)

11895481
16289059

Gene Ontology  (GO ID)

Biological Process

GO:0060348  bone development
GO:0001502  cartilage condensation
GO:0051216  cartilage development
GO:0007155  cell adhesion
GO:0002063  chondrocyte development
GO:0048706  embryonic skeletal system development
GO:0014846  esophagus smooth muscle contraction
GO:0032836  glomerular basement membrane development
GO:0003094  glomerular filtration
GO:0030201  heparan sulfate proteoglycan metabolic process
GO:0060384  innervation
GO:0001822  kidney development
GO:0008152  metabolic process
GO:0016525  negative regulation of angiogenesis
GO:0030336  negative regulation of cell migration
GO:0001937  negative regulation of endothelial cell proliferation
GO:0040037  negative regulation of fibroblast growth factor receptor signaling pathway
GO:0060686  negative regulation of prostatic bud formation
GO:0030513  positive regulation of BMP signaling pathway
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0010575  positive regulation vascular endothelial growth factor production
GO:0040036  regulation of fibroblast growth factor receptor signaling pathway
GO:0048010  vascular endothelial growth factor receptor signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0005783  endoplasmic reticulum
GO:0005615  extracellular space
GO:0005794  Golgi apparatus
GO:0005795  Golgi stack
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0018741  alkyl sulfatase activity
GO:0004065  arylsulfatase activity
GO:0005509  calcium ion binding
GO:0008449  N-acetylglucosamine-6-sulfatase activity