cytochrome P450, subfamily 21A, polypeptide 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:147.20 bone:- skin:-
GeneChip cerebrum:7.94 cerebellum:7.79 brain stem:7.84 corpus callosum/glia:- pineal gland:- peripheral nerve:7.69 spine:- retina:- eye:8.11 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.76 thymus:7.70 bone marrow:7.71 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.86 muscle:8.06 esophagus:- stomach:- intestine:7.85 colon:7.61 liver/hepato:- lung:- bladder:- kidney:7.84 pituitary:8.11 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_057101
Gene ID 24298
Unigene ID Rn.161726
Probe set ID U56853_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000000428

Orthologous Gene

Human[2]  NM_000500, NM_001128590
Mouse[2]  NM_009995, NM_001128590

Chromosomal Region

20p12  [4,125,357  -  4,128,518]

Gene Family (Interpro ID)

IPR001128  Cytochrome P450
IPR002397  Cytochrome P450, B-class
IPR002401  Cytochrome P450, E-class, group I
IPR008066  Cytochrome P450, E-class, group I, CYP1
IPR002403  Cytochrome P450, E-class, group IV

Link to Pubmed  (Pubmed ID)

7588239
9408081
12136338
12930931
14519458
15060004
15583024
19665544
19733641

Gene Ontology  (GO ID)

Biological Process

GO:0006700  C21-steroid hormone biosynthetic process
GO:0071375  cellular response to peptide hormone stimulus
GO:0006705  mineralocorticoid biosynthetic process
GO:0042448  progesterone metabolic process
GO:0046677  response to antibiotic

Cellular Component

GO:0005789  endoplasmic reticulum membrane

Molecular Function

GO:0009055  electron carrier activity
GO:0020037  heme binding
GO:0005506  iron ion binding
GO:0004497  monooxygenase activity
GO:0016705  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0004509  steroid 21-monooxygenase activity
GO:0005496  steroid binding