glutamate receptor, ionotropic, kainate 5

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:147.20 bone:- skin:-
GeneChip cerebrum:8.53 cerebellum:8.15 brain stem:8.38 corpus callosum/glia:- pineal gland:- peripheral nerve:8.78 spine:- retina:- eye:8.15 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.42 thymus:7.57 bone marrow:7.49 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:113.90 ovary:- testis:82.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:177.70 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.41 muscle:7.60 esophagus:- stomach:- intestine:7.44 colon:7.38 liver/hepato:- lung:- bladder:- kidney:7.53 pituitary:7.54 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_031508
Gene ID 24407
Unigene ID Rn.74042
Probe set ID Z11581_at  [RG_U34A]
Ensembl ID ENSRNOG00000020310

Orthologous Gene

Human[2]  NM_002088
Mouse[1]  NM_008168

Chromosomal Region

1q21  [80,313,806  -  80,384,390]

Gene Family (Interpro ID)

IPR001828  Extracellular ligand-binding receptor
IPR001638  Extracellular solute-binding protein, family 3
IPR001320  Ionotropic glutamate receptor
IPR001508  NMDA receptor

Link to Pubmed  (Pubmed ID)

1127911
1322826
1371217
1373632
9259378
9390526
9808460
9848088
10627597
11226670
12080343
12477932
12878702
15796762
15844209
16360275
16903873
16936133
17110338
17639597
18096442
22114280
22509486
23288040
23975096

Gene Ontology  (GO ID)

Biological Process

GO:0071333  cellular response to glucose stimulus
GO:0051649  establishment of localization in cell
GO:0035235  ionotropic glutamate receptor signaling pathway
GO:0043525  positive regulation of neuron apoptosis
GO:0006621  protein retention in ER lumen
GO:0043113  receptor clustering
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0042391  regulation of membrane potential
GO:0031630  regulation of synaptic vesicle fusion to presynaptic membrane
GO:0007268  synaptic transmission
GO:0035249  synaptic transmission, glutamatergic

Cellular Component

GO:0030424  axon
GO:0030054  cell junction
GO:0043025  cell soma
GO:0030425  dendrite
GO:0008328  ionotropic glutamate receptor complex
GO:0032983  kainate selective glutamate receptor complex
GO:0016020  membrane
GO:0043005  neuron projection
GO:0043204  perikaryon
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0042734  presynaptic membrane
GO:0043195  terminal button

Molecular Function

GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0008066  glutamate receptor activity
GO:0042802  identical protein binding
GO:0015277  kainate selective glutamate receptor activity
GO:0030165  PDZ domain binding
GO:0005515  protein binding
GO:0017124  SH3 domain binding