ATP-binding cassette, sub-family C (CFTR/MRP), member 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.04 cerebellum:6.34 brain stem:6.25 corpus callosum/glia:- pineal gland:- peripheral nerve:5.56 spine:- retina:- eye:6.01 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.63 thymus:5.55 bone marrow:5.76 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5.29 muscle:5.78 esophagus:- stomach:- intestine:5.28 colon:5.29 liver/hepato:- lung:- bladder:- kidney:5.66 pituitary:6.40 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_022281
Gene ID 24565
Unigene ID Rn.104959
Probe set ID X96394_at  [RG_U34A]
Ensembl ID ENSRNOG00000032748

Orthologous Gene

Human[10]  NM_004996, NM_019862, NM_019898, NM_019899, NM_019900
Mouse[2]  NM_008576, NM_019862, NM_019898, NM_019899, NM_019900

Chromosomal Region

10q11  [452,239  -  575,705]

Gene Family (Interpro ID)

IPR017940  ABC transporter integral membrane type 1
IPR001140  ABC transporter, transmembrane domain
IPR011527  ABC transporter, transmembrane domain, type 1
IPR003439  ABC transporter-like
IPR003593  ATPase, AAA+ type, core

Link to Pubmed  (Pubmed ID)

8662992
11208926
11238654
11689020
11804835
12125073
12423064
12433976
12867490
12893836
12930913
14623264
14641820
15198509
15328029
16170839
16868918
16946557
17050692
17072643
17141959
17669244
17854063
18057958
18290326
18465260
18485102
18509883
18680196
18931056
19053318
19879335
19897579
20051532
20487524
21297965
21495913
21803151
22015764
22563480
22883408
23474709
23940624

Gene Ontology  (GO ID)

Biological Process

GO:0006200  ATP catabolic process
GO:0060326  cell chemotaxis
GO:0043215  daunorubicin transport
GO:0046618  drug export
GO:0034775  glutathione transmembrane transport
GO:0006855  multidrug transport
GO:0033700  phospholipid efflux
GO:0015911  plasma membrane long-chain fatty acid transport
GO:0030335  positive regulation of cell migration
GO:0042493  response to drug
GO:0006979  response to oxidative stress
GO:0055085  transmembrane transport
GO:0042908  xenobiotic transport

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0005737  cytoplasm
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0016887  ATPase activity
GO:0042626  ATPase activity, coupled to transmembrane movement of substances
GO:0015238  drug transporter activity
GO:0015562  efflux transmembrane transporter activity
GO:0015431  glutathione S-conjugate-exporting ATPase activity
GO:0034634  glutathione transmembrane transporter activity
GO:0034040  lipid-transporting ATPase activity
GO:0005324  long-chain fatty acid transporter activity
GO:0016491  oxidoreductase activity
GO:0046624  sphingolipid transporter activity
GO:0008559  xenobiotic-transporting ATPase activity