protein tyrosine phosphatase, receptor type, C

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:248.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:546 thymus:1106.20 bone marrow:- adipose:- bone:156.20 skin:-
GeneChip cerebrum:5.43 cerebellum:5.35 brain stem:5.65 corpus callosum/glia:- pineal gland:- peripheral nerve:5.11 spine:- retina:- eye:5.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.69 thymus:6.66 bone marrow:6.79 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:113.90 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:289.90     liver/hepato:13.30        lung:304    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:227.60 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5.63 muscle:5.48 esophagus:- stomach:- intestine:5.68 colon:5.44 liver/hepato:- lung:- bladder:- kidney:5.48 pituitary:5.34 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001109888
Gene ID 24699
Unigene ID Rn.90166
Probe set ID M10072mRNA_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000000655

Orthologous Gene

Human[7]  NM_002838, NM_080921, NM_080923
Mouse[2]  NM_001111316, NM_011210, NM_080923

Chromosomal Region

13q13  [51,246,164  -  51,357,995]

Gene Family (Interpro ID)

IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR000242  Protein-tyrosine phosphatase, receptor/non-receptor type

Link to Pubmed  (Pubmed ID)

2440674
3158393
8889548
10814697
10941847
11101853
11145714
12115612
12496963
16263122
17290791
19356234
21151953
21166153
22871113

Gene Ontology  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0030183  B cell differentiation
GO:0042100  B cell proliferation
GO:0050853  B cell receptor signaling pathway
GO:0048539  bone marrow development
GO:0051607  defense response to virus
GO:0016311  dephosphorylation
GO:0002244  hemopoietic progenitor cell differentiation
GO:0034113  heterotypic cell-cell adhesion
GO:0002378  immunoglobulin biosynthetic process
GO:0007159  leukocyte adhesion
GO:0006933  negative regulation of cell adhesion involved in substrate-bound cell migration
GO:0001960  negative regulation of cytokine-mediated signaling pathway
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0031953  negative regulation of protein amino acid autophosphorylation
GO:0006469  negative regulation of protein kinase activity
GO:0001915  negative regulation of T cell mediated cytotoxicity
GO:0045060  negative thymic T cell selection
GO:0046641  positive regulation of alpha-beta T cell proliferation
GO:0050857  positive regulation of antigen receptor-mediated signaling pathway
GO:0043065  positive regulation of apoptosis
GO:0030890  positive regulation of B cell proliferation
GO:0045588  positive regulation of gamma-delta T cell differentiation
GO:0002925  positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0048304  positive regulation of isotype switching to IgG isotypes
GO:0043410  positive regulation of MAPKKK cascade
GO:0045582  positive regulation of T cell differentiation
GO:0001916  positive regulation of T cell mediated cytotoxicity
GO:0002711  positive regulation of T cell mediated immunity
GO:0042102  positive regulation of T cell proliferation
GO:0045059  positive thymic T cell selection
GO:0006470  protein amino acid dephosphorylation
GO:0045577  regulation of B cell differentiation
GO:0050855  regulation of B cell receptor signaling pathway
GO:0051726  regulation of cell cycle
GO:0002923  regulation of humoral immune response mediated by circulating immunoglobulin
GO:0033261  regulation of S phase
GO:0051209  release of sequestered calcium ion into cytosol
GO:0010332  response to gamma radiation
GO:0048864  stem cell development
GO:0030217  T cell differentiation
GO:0042098  T cell proliferation
GO:0050852  T cell receptor signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0009897  external side of plasma membrane
GO:0005925  focal adhesion
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0009898  internal side of plasma membrane
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0043395  heparan sulfate proteoglycan binding
GO:0008201  heparin binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0019887  protein kinase regulator activity
GO:0004725  protein tyrosine phosphatase activity
GO:0005001  transmembrane receptor protein tyrosine phosphatase activity