suppressor of cytokine signaling 1

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:96.90 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_145879
Gene ID 252971
Unigene ID Rn.82754
Probe set ID -
Ensembl ID ENSRNOG00000002568

Orthologous Gene

Human[2]  NM_003745
Mouse[1]  NM_009896

Chromosomal Region

10q11  [4,819,971  -  4,820,609]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8720108
10679190
11027633
11312157
11342531
11867182
12039028
12584205
12644450
12888825
14522994
15169905
15240880
15361843
16242928
16377761
16458425
16878360
16956890
17010638
17522834
18171911
18325991
18381452
18424750
18843197
19080716
19100470
19135225
19176113
19344732
20185635
20519071
20519645
20832564
21364493
21742974
22302831
22875468
23222907
24091940
24660535

Gene Ontology  (GO ID)

Biological Process

GO:0071230  cellular response to amino acid stimulus
GO:0019221  cytokine-mediated signaling pathway
GO:0045444  fat cell differentiation
GO:0007259  JAK-STAT cascade
GO:0043086  negative regulation of catalytic activity
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0046426  negative regulation of JAK-STAT cascade
GO:0009968  negative regulation of signal transduction
GO:0042518  negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0031100  organ regeneration
GO:0016567  protein ubiquitination
GO:0040008  regulation of growth
GO:0001932  regulation of protein amino acid phosphorylation
GO:0034097  response to cytokine stimulus
GO:0042493  response to drug
GO:0032355  response to estradiol stimulus
GO:0032496  response to lipopolysaccharide
GO:0043434  response to peptide hormone stimulus
GO:0032570  response to progesterone stimulus

Cellular Component

GO:0005575  cellular_component
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005634  nucleus

Molecular Function

GO:0005159  insulin-like growth factor receptor binding
GO:0019210  kinase inhibitor activity
GO:0003674  molecular_function
GO:0019901  protein kinase binding