TIMP metallopeptidase inhibitor 3

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:227.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:221.20 spine:- retina:- eye:142.20 artery/aorta:357.10 vein:- lymphnode:- peripheral blood:- spleen:390 thymus:245.80 bone marrow:- adipose:588.80 bone:390.50 skin:235.40
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:1593 prostate:151.80 ovary:342.30 testis:- heart:135.70 muscle:- esophagus:- stomach:- intestine:209.30 colon:-     liver/hepato:-        lung:202.60    bladder:- kidney:63.80 pituitary:118.40 thyroid/parathyroid:3891.10 adrenal gland:- pancreas:284.50 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001075779
Gene ID 25358
Unigene ID Rn.119634
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

7q13  [19,677,156  -  19,727,072]

Gene Family (Interpro ID)

IPR001134  Netrin domain
IPR001820  Proteinase inhibitor I35, tissue inhibitor of metalloproteinase
IPR008993  TIMP-like, OB-fold

Link to Pubmed  (Pubmed ID)

8654952
8840279
9400791
11004090
11044612
11576837
11827969
11984824
12444073
12477932
12798711
12828172
15052653
15217927
15507671
15866537
15878627
15928670
16256342
16683235
16736496
17009974
17032447
17083784
17275272
17532789
17551674
17555880
17717962
17976707
18082200
18156304
18205041
18278151
18636553
18993041
19389837
19633828
20889352
24560960

Gene Ontology  (GO ID)

Biological Process

GO:0007568  aging
GO:0071310  cellular response to organic substance
GO:0007417  central nervous system development
GO:0006917  induction of apoptosis
GO:0051045  negative regulation of membrane protein ectodomain proteolysis
GO:0045861  negative regulation of proteolysis
GO:0043200  response to amino acid stimulus
GO:0043627  response to estrogen stimulus
GO:0051593  response to folic acid
GO:0009725  response to hormone stimulus
GO:0009612  response to mechanical stimulus
GO:0014070  response to organic cyclic substance
GO:0010033  response to organic substance
GO:0042246  tissue regeneration

Cellular Component

GO:0005604  basement membrane
GO:0005737  cytoplasm
GO:0031012  extracellular matrix
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0046872  metal ion binding
GO:0008191  metalloendopeptidase inhibitor activity