noggin

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:71.10 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:122.90 bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.78 cerebellum:4.25 brain stem:3.87 corpus callosum/glia:- pineal gland:- peripheral nerve:3.58 spine:- retina:- eye:3.77 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:3.01 thymus:3.07 bone marrow:3.18 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:63.80 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:3.15 muscle:3.24 esophagus:- stomach:- intestine:3.16 colon:3.30 liver/hepato:- lung:- bladder:- kidney:3.07 pituitary:4.08 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_012990
Gene ID 25495
Unigene ID Rn.101545
Probe set ID rc_AA859752_at  [RG_U34A]
Ensembl ID ENSRNOG00000023683

Orthologous Gene

Human[1]  NM_005450
Mouse[1]  NM_008711

Chromosomal Region

10q26  [77,689,924  -  77,690,622]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7666191
8889548
10080184
14643011
14975730
15199066
15252029
16828469
17258709
21238590
21447372

Gene Ontology  (GO ID)

Biological Process

GO:0048646  anatomical structure formation involved in morphogenesis
GO:0048318  axial mesoderm development
GO:0007411  axon guidance
GO:0030509  BMP signaling pathway
GO:0007420  brain development
GO:0051216  cartilage development
GO:0021533  cell differentiation in hindbrain
GO:0007417  central nervous system development
GO:0009953  dorsal/ventral pattern formation
GO:0042733  embryonic digit morphogenesis
GO:0060272  embryonic skeletal joint morphogenesis
GO:0048706  embryonic skeletal system development
GO:0001706  endoderm formation
GO:0001837  epithelial to mesenchymal transition
GO:0060325  face morphogenesis
GO:0060825  fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0030900  forebrain development
GO:0001701  in utero embryonic development
GO:0060173  limb development
GO:0060425  lung morphogenesis
GO:0048762  mesenchymal cell differentiation
GO:0001707  mesoderm formation
GO:0042474  middle ear morphogenesis
GO:0008045  motor axon guidance
GO:0043066  negative regulation of apoptosis
GO:0048712  negative regulation of astrocyte differentiation
GO:0030514  negative regulation of BMP signaling pathway
GO:0060044  negative regulation of cardiac muscle cell proliferation
GO:0030336  negative regulation of cell migration
GO:0060302  negative regulation of cytokine activity
GO:0045668  negative regulation of osteoblast differentiation
GO:0060394  negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0001839  neural plate morphogenesis
GO:0001843  neural tube closure
GO:0021915  neural tube development
GO:0048570  notochord morphogenesis
GO:0001649  osteoblast differentiation
GO:0007389  pattern specification process
GO:0021983  pituitary gland development
GO:0090190  positive regulation of branching involved in ureteric bud morphogenesis
GO:0050679  positive regulation of epithelial cell proliferation
GO:0090193  positive regulation of glomerulus development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0060513  prostatic bud formation
GO:0030510  regulation of BMP signaling pathway
GO:0045664  regulation of neuron differentiation
GO:0001501  skeletal system development
GO:0035019  somatic stem cell maintenance
GO:0021510  spinal cord development
GO:0001657  ureteric bud development
GO:0060676  ureteric bud formation
GO:0001655  urogenital system development
GO:0042060  wound healing

Cellular Component

GO:0005575  cellular_component
GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0019955  cytokine binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0042803  protein homodimerization activity