Notch homolog 1, translocation-associated (Drosophila)

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Synonym

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Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:35.50 artery/aorta:357.10 vein:- lymphnode:- peripheral blood:- spleen:312 thymus:- bone marrow:- adipose:147.20 bone:78.10 skin:-
GeneChip cerebrum:6.72 cerebellum:6.51 brain stem:6.60 corpus callosum/glia:- pineal gland:- peripheral nerve:6.39 spine:- retina:- eye:7.41 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.05 thymus:5.96 bone marrow:6.03 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:151.80 ovary:- testis:- heart:58.20 muscle:- esophagus:- stomach:- intestine:104.70 colon:289.90     liver/hepato:-        lung:253.30    bladder:- kidney:63.80 pituitary:296.10 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6.21 muscle:6.27 esophagus:- stomach:- intestine:6.44 colon:6.12 liver/hepato:- lung:- bladder:- kidney:6.46 pituitary:5.97 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001105721
Gene ID 25496
Unigene ID Rn.25046
Probe set ID X57405_at  [RG_U34A]
Ensembl ID ENSRNOG00000019322

Orthologous Gene

Human[1]  NM_017617
Mouse[4]  NM_008714

Chromosomal Region

3p13  [4,631,808  -  4,675,880]

Gene Family (Interpro ID)

IPR013091  EGF calcium-binding
IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3

Link to Pubmed  (Pubmed ID)

1295745
1764995
11078798
11182080
11438922
11700865
11900468
11997524
12489191
12727209
12853432
12876431
15057910
15058751
15082708
15247148
15472075
15887117
15920012
16025100
16048523
16094703
16378597
16680150
16707600
16738328
16838279
16949068
17091491
17157832
17217625
17297654
17393108
17543552
17761886
17855369
18311147
18411251
18449946
18662245
18685078
18781453
18824567
18927449
18942116
19028876
19080462
19109527
19143760
19238999
19336246
19378247
19407245
19481073
19481784
19489437
19536070
19587430
19698832
19828677
20056840
20195794
20333303
20484026
20730910
21209419
21330605
21426641
21672385
21887253
22085497
22110751
22302604
22334042
22474986
22525134
22713619
22833359
22833673
22964414
22989188
23056328
23132739
23232913
23589286
23595520
23707238
23755752
23834718
23844238
23938602
24098939
24397211
24751889

Gene Ontology  (GO ID)

Biological Process

GO:0042640  anagen
GO:0001525  angiogenesis
GO:0003180  aortic valve morphogenesis
GO:0060842  arterial endothelial cell differentiation
GO:0048708  astrocyte differentiation
GO:0003162  atrioventricular node development
GO:0003181  atrioventricular valve morphogenesis
GO:0009912  auditory receptor cell fate commitment
GO:0007409  axonogenesis
GO:0048754  branching morphogenesis of a tube
GO:0003209  cardiac atrium morphogenesis
GO:0003207  cardiac chamber formation
GO:0060317  cardiac epithelial to mesenchymal transition
GO:0003214  cardiac left ventricle morphogenesis
GO:0060038  cardiac muscle cell proliferation
GO:0055008  cardiac muscle tissue morphogenesis
GO:0003213  cardiac right atrium morphogenesis
GO:0003219  cardiac right ventricle formation
GO:0060411  cardiac septum morphogenesis
GO:0060948  cardiac vascular smooth muscle cell development
GO:0003208  cardiac ventricle morphogenesis
GO:0030154  cell differentiation
GO:0021515  cell differentiation in spinal cord
GO:0045165  cell fate commitment
GO:0001708  cell fate specification
GO:0003273  cell migration involved in endocardial cushion formation
GO:0071372  cellular response to follicle-stimulating hormone stimulus
GO:0007386  compartment specification
GO:0060982  coronary artery morphogenesis
GO:0003169  coronary vein morphogenesis
GO:0007368  determination of left/right symmetry
GO:0009790  embryonic development
GO:0035116  embryonic hindlimb morphogenesis
GO:0030326  embryonic limb morphogenesis
GO:0060956  endocardial cell differentiation
GO:0003203  endocardial cushion morphogenesis
GO:0003157  endocardium development
GO:0003160  endocardium morphogenesis
GO:0007492  endoderm development
GO:0008544  epidermis development
GO:0001837  epithelial to mesenchymal transition
GO:0003198  epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0030900  forebrain development
GO:0007440  foregut morphogenesis
GO:0010001  glial cell differentiation
GO:0003241  growth involved in heart morphogenesis
GO:0031069  hair follicle morphogenesis
GO:0007507  heart development
GO:0001947  heart looping
GO:0006959  humoral immune response
GO:0001701  in utero embryonic development
GO:0002437  inflammatory response to antigenic stimulus
GO:0030216  keratinocyte differentiation
GO:0070986  left/right axis specification
GO:0001889  liver development
GO:0030324  lung development
GO:0014031  mesenchymal cell development
GO:0003192  mitral valve formation
GO:0030514  negative regulation of BMP signaling pathway
GO:0045955  negative regulation of calcium ion-dependent exocytosis
GO:0043086  negative regulation of catalytic activity
GO:0060548  negative regulation of cell death
GO:0045596  negative regulation of cell differentiation
GO:0090051  negative regulation of cell migration involved in sprouting angiogenesis
GO:0008285  negative regulation of cell proliferation
GO:0010812  negative regulation of cell-substrate adhesion
GO:0060253  negative regulation of glial cell proliferation
GO:0045662  negative regulation of myoblast differentiation
GO:0010832  negative regulation of myotube differentiation
GO:0050768  negative regulation of neurogenesis
GO:0045665  negative regulation of neuron differentiation
GO:0048715  negative regulation of oligodendrocyte differentiation
GO:0030279  negative regulation of ossification
GO:0045668  negative regulation of osteoblast differentiation
GO:0046533  negative regulation of photoreceptor cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0021915  neural tube development
GO:0030182  neuron differentiation
GO:0048663  neuron fate commitment
GO:0007219  Notch signaling pathway
GO:0048709  oligodendrocyte differentiation
GO:0031100  organ regeneration
GO:0003344  pericardium morphogenesis
GO:0043065  positive regulation of apoptosis
GO:0048711  positive regulation of astrocyte differentiation
GO:0030513  positive regulation of BMP signaling pathway
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0045603  positive regulation of endothelial cell differentiation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0045687  positive regulation of glial cell differentiation
GO:0046427  positive regulation of JAK-STAT cascade
GO:0045618  positive regulation of keratinocyte differentiation
GO:0002052  positive regulation of neuroblast proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0007221  positive regulation of transcription of Notch receptor target
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0060740  prostate gland epithelium morphogenesis
GO:0003184  pulmonary valve morphogenesis
GO:0003264  regulation of cardioblast proliferation
GO:0030334  regulation of cell migration
GO:0042127  regulation of cell proliferation
GO:0050678  regulation of epithelial cell proliferation
GO:0060768  regulation of epithelial cell proliferation involved in prostate gland development
GO:0010468  regulation of gene expression
GO:0050767  regulation of neurogenesis
GO:0003270  regulation of second heart field cardioblast proliferation by Notch signaling pathway
GO:0014807  regulation of somitogenesis
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0003256  regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0031960  response to corticosteroid stimulus
GO:0032496  response to lipopolysaccharide
GO:0032495  response to muramyl dipeptide
GO:0060528  secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0048103  somatic stem cell division
GO:0007283  spermatogenesis
GO:0002040  sprouting angiogenesis
GO:0042246  tissue regeneration
GO:0006351  transcription, DNA-dependent
GO:0035148  tube lumen formation
GO:0060979  vasculogenesis involved in coronary vascular morphogenesis
GO:0060843  venous endothelial cell differentiation
GO:0060412  ventricular septum morphogenesis
GO:0003222  ventricular trabecular myocardium morphogenesis

Cellular Component

GO:0001669  acrosomal vesicle
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0030027  lamellipodium
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0001726  ruffle

Molecular Function

GO:0005509  calcium ion binding
GO:0003682  chromatin binding
GO:0031490  chromatin DNA binding
GO:0019899  enzyme binding
GO:0004857  enzyme inhibitor activity
GO:0004872  receptor activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity