FK506 binding protein 1a

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:191.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:516.20 spine:- retina:- eye:213.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:234 thymus:737.50 bone marrow:- adipose:147.20 bone:195.20 skin:470.80
GeneChip cerebrum:9.40 cerebellum:8.98 brain stem:9.01 corpus callosum/glia:- pineal gland:- peripheral nerve:10.23 spine:- retina:- eye:7.16 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:8.43 thymus:9.37 bone marrow:7.97 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:238.90 prostate:189.80 ovary:456.50 testis:82.30 heart:504.10 muscle:531.50 esophagus:- stomach:- intestine:- colon:-     liver/hepato:133        lung:506.60    bladder:- kidney:191.40 pituitary:236.90 thyroid/parathyroid:- adrenal gland:- pancreas:170.70 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:8.59 muscle:8.49 esophagus:- stomach:- intestine:8.05 colon:8.37 liver/hepato:- lung:- bladder:- kidney:7.65 pituitary:8.12 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_013102
Gene ID 25639
Unigene ID Rn.80611
Probe set ID rc_AA875594_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000008822

Orthologous Gene

Human[16]  NM_000801, NM_054014
Mouse[8]  NM_008019, NM_054014

Chromosomal Region

3q41  [141,861,237  -  141,880,796]

Gene Family (Interpro ID)

IPR001179  Peptidyl-prolyl cis-trans isomerase, FKBP-type

Link to Pubmed  (Pubmed ID)

7518616
8941644
9013543
9461216
12477932
12494287
12809600
15489334
17313373
17546681
17877381
17921453
17962721
18684528
21255728
22363773
22871113

Gene Ontology  (GO ID)

Biological Process

GO:0034205  beta-amyloid formation
GO:0019221  cytokine-mediated signaling pathway
GO:0043206  fibril organization
GO:0003007  heart morphogenesis
GO:0060347  heart trabecula formation
GO:0006936  muscle contraction
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0032513  negative regulation of protein phosphatase type 2B activity
GO:0051280  negative regulation of release of sequestered calcium ion into cytosol
GO:0060315  negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0018208  peptidyl-proline modification
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032092  positive regulation of protein binding
GO:0031398  positive regulation of protein ubiquitination
GO:0006457  protein folding
GO:0000413  protein peptidyl-prolyl isomerization
GO:0032925  regulation of activin receptor signaling pathway
GO:0050776  regulation of immune response
GO:0060314  regulation of ryanodine-sensitive calcium-release channel activity
GO:0051209  release of sequestered calcium ion into cytosol
GO:0031000  response to caffeine
GO:0010039  response to iron ion
GO:0007183  SMAD protein complex assembly
GO:0042098  T cell proliferation
GO:0055010  ventricular cardiac muscle tissue morphogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0043679  nerve terminal
GO:0033017  sarcoplasmic reticulum membrane
GO:0030018  Z disc

Molecular Function

GO:0048185  activin binding
GO:0019855  calcium channel inhibitor activity
GO:0008144  drug binding
GO:0019899  enzyme binding
GO:0005528  FK506 binding
GO:0030544  Hsp70 protein binding
GO:0003755  peptidyl-prolyl cis-trans isomerase activity
GO:0005515  protein binding
GO:0004871  signal transducer activity
GO:0046332  SMAD binding
GO:0005160  transforming growth factor beta receptor binding
GO:0034713  type I transforming growth factor beta receptor binding