discoidin domain receptor tyrosine kinase 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.83 cerebellum:6.76 brain stem:7.04 corpus callosum/glia:- pineal gland:- peripheral nerve:6.93 spine:- retina:- eye:7.62 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.46 thymus:6.71 bone marrow:6.67 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:721.20 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6.94 muscle:6.84 esophagus:- stomach:- intestine:6.84 colon:6.57 liver/hepato:- lung:- bladder:- kidney:6.72 pituitary:6.80 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_013137
Gene ID 25678
Unigene ID Rn.78071
Probe set ID L26525_at  [RG_U34A]
Ensembl ID ENSRNOG00000000830

Orthologous Gene

Human[12]  NM_001202521, NM_001202523, NM_001954, NM_013993, NM_013994
Mouse[10]  NM_001198831, NM_001198833, NM_007584, NM_172962, NM_013994

Chromosomal Region

20p12  [3,196,658  -  3,214,886]

Gene Family (Interpro ID)

IPR000421  Coagulation factor 5/8 type, C-terminal
IPR008957  Fibronectin, type III-like fold
IPR008979  Galactose-binding domain-like
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8127887
11304604
12477932
15218324
16472941
16497176
24018687

Gene Ontology  (GO ID)

Biological Process

GO:0060444  branching involved in mammary gland duct morphogenesis
GO:0043583  ear development
GO:0007566  embryo implantation
GO:0007565  female pregnancy
GO:0007595  lactation
GO:0060749  mammary gland alveolus development
GO:0008285  negative regulation of cell proliferation
GO:0031100  organ regeneration
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0046777  protein amino acid autophosphorylation
GO:0001558  regulation of cell growth
GO:0001952  regulation of cell-matrix adhesion
GO:0010715  regulation of extracellular matrix disassembly
GO:0043588  skin development
GO:0014909  smooth muscle cell migration

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0005518  collagen binding
GO:0046872  metal ion binding
GO:0003674  molecular_function