STIP1 homology and U-Box containing protein 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:213.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:75.90 ovary:- testis:- heart:96.90 muscle:265.70 esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001025625
Gene ID 287155
Unigene ID Rn.65040
Probe set ID -
Ensembl ID ENSRNOG00000019798

Orthologous Gene

Human[1]  NM_005861
Mouse[2]  NM_019719

Chromosomal Region

10q12  [15,096,151  -  15,098,431]

Gene Family (Interpro ID)

IPR019734  Tetratricopeptide repeat
IPR001440  Tetratricopeptide TPR-1
IPR013105  Tetratricopeptide TPR2
IPR003613  U box domain
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

8889548
12477932
15671027
18301957
19237536
19483080
19953350
20413784
20724525
20819951
21219885
21808025
22267842
22456997
24186360
24334056

Gene Ontology  (GO ID)

Biological Process

GO:0071218  cellular response to misfolded protein
GO:0006515  misfolded or incompletely synthesized protein catabolic process
GO:0090035  positive regulation of cellular chaperone-mediated protein complex assembly
GO:0032436  positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031398  positive regulation of protein ubiquitination
GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0051865  protein autoubiquitination
GO:0070534  protein K63-linked ubiquitination
GO:0000209  protein polyubiquitination
GO:0031943  regulation of glucocorticoid metabolic process
GO:0006511  ubiquitin-dependent protein catabolic process
GO:0030579  ubiquitin-dependent SMAD protein catabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0042405  nuclear inclusion body
GO:0000151  ubiquitin ligase complex

Molecular Function

GO:0019899  enzyme binding
GO:0030544  Hsp70 protein binding
GO:0051879  Hsp90 protein binding
GO:0019900  kinase binding
GO:0051787  misfolded protein binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0046332  SMAD binding
GO:0030911  TPR domain binding
GO:0031625  ubiquitin protein ligase binding
GO:0004842  ubiquitin-protein ligase activity
GO:0034450  ubiquitin-ubiquitin ligase activity