serine hydroxymethyltransferase 1 (soluble)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:122.90 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:238.90 prostate:38 ovary:342.30 testis:82.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:26.60        lung:50.70    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:170.70 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001047842
Gene ID 287379
Unigene ID Rn.36848
Probe set ID -
Ensembl ID ENSRNOG00000005275

Orthologous Gene

Human[4]  NM_004169, NM_148918
Mouse[4]  NM_009171, NM_148918

Chromosomal Region

10q22  [46,936,605  -  46,964,779]

Gene Family (Interpro ID)

IPR015424  Pyridoxal phosphate-dependent transferase, major domain

Link to Pubmed  (Pubmed ID)

3110140
12138190
12477932
15598699
15671219
17031801
17311260
17896178
22108709
22332074
23106098

Gene Ontology  (GO ID)

Biological Process

GO:0046655  folic acid metabolic process
GO:0006545  glycine biosynthetic process
GO:0019264  glycine biosynthetic process from serine
GO:0006544  glycine metabolic process
GO:0006565  L-serine catabolic process
GO:0006563  L-serine metabolic process
GO:0051289  protein homotetramerization
GO:0051262  protein tetramerization
GO:0009113  purine base biosynthetic process

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0016597  amino acid binding
GO:0004372  glycine hydroxymethyltransferase activity
GO:0042802  identical protein binding
GO:0008732  L-allo-threonine aldolase activity
GO:0042803  protein homodimerization activity
GO:0030170  pyridoxal phosphate binding