serine (or cysteine) peptidase inhibitor, clade F, member 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:122.90 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:38 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:505.30        lung:-    bladder:- kidney:701.90 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001011892
Gene ID 287527
Unigene ID Rn.15774
Probe set ID -
Ensembl ID ENSRNOG00000003233

Orthologous Gene

Human[3]  NM_000934, NM_001165920, NM_001165921
Mouse[1]  NM_008878, NM_001165920, NM_001165921

Chromosomal Region

10q24  [62,748,116  -  62,756,200]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1334334
1384011
2313941
2438835
6121140
6438828
6506034
8624776
9184412
9207984
9361364
10423332
10583218
12477932
12595617
12911586
15771120
19073825

Gene Ontology  (GO ID)

Biological Process

GO:0048514  blood vessel morphogenesis
GO:0030199  collagen fibril organization
GO:0010951  negative regulation of endopeptidase activity
GO:0051918  negative regulation of fibrinolysis
GO:0010757  negative regulation of plasminogen activation
GO:0045597  positive regulation of cell differentiation
GO:0032967  positive regulation of collagen biosynthetic process
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0046330  positive regulation of JNK cascade
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0051496  positive regulation of stress fiber formation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0002034  regulation of blood vessel size by renin-angiotensin
GO:0030162  regulation of proteolysis
GO:0010033  response to organic substance

Cellular Component

GO:0009986  cell surface
GO:0005615  extracellular space
GO:0005577  fibrinogen complex

Molecular Function

GO:0002020  protease binding
GO:0042803  protein homodimerization activity
GO:0004867  serine-type endopeptidase inhibitor activity