NACHT, leucine rich repeat and PYD containing 12

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001066862
Gene ID 292541
Unigene ID Rn.108865
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

1q12  [64,242,875  -  64,270,936]

Gene Family (Interpro ID)

IPR003593  ATPase, AAA+ type, core
IPR011029  DEATH-like
IPR004020  Pyrin

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0050710  negative regulation of cytokine secretion
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050728  negative regulation of inflammatory response
GO:0050711  negative regulation of interleukin-1 secretion
GO:0045409  negative regulation of interleukin-6 biosynthetic process
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0031953  negative regulation of protein amino acid autophosphorylation
GO:0009968  negative regulation of signal transduction
GO:0045751  negative regulation of Toll signaling pathway
GO:0008588  release of cytoplasmic sequestered NF-kappaB

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0005524  ATP binding