phosphoinositide-3-kinase adaptor protein 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.90 cerebellum:- brain stem:5102 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:4444.40 eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:113.90 ovary:114.10 testis:82.30 heart:- muscle:- esophagus:- stomach:- intestine:104.70 colon:-     liver/hepato:93.10        lung:152    bladder:- kidney:319 pituitary:59.20 thyroid/parathyroid:- adrenal gland:6535.90 pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_220008
Gene ID 294048
Unigene ID Rn.15411
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

1q54  [246,474,789  -  246,534,688]

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR003980  Histamine H3 receptor

Link to Pubmed  (Pubmed ID)

12477932

Gene Ontology  (GO ID)

Biological Process

GO:0034122  negative regulation of toll-like receptor signaling pathway
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0034123  positive regulation of toll-like receptor signaling pathway
GO:0043122  regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050727  regulation of inflammatory response
GO:0043408  regulation of MAPKKK cascade
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034154  toll-like receptor 7 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0042802  identical protein binding
GO:0016301  kinase activity