DNA-damage inducible transcript 3

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:106.60 artery/aorta:357.10 vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:156.20 skin:-
GeneChip cerebrum:6.49 cerebellum:6.66 brain stem:7.23 corpus callosum/glia:- pineal gland:- peripheral nerve:6.59 spine:- retina:- eye:5.98 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.37 thymus:6.80 bone marrow:6.29 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:75.90 ovary:- testis:- heart:116.30 muscle:- esophagus:- stomach:- intestine:104.70 colon:289.90     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.38 muscle:6.56 esophagus:- stomach:- intestine:6.36 colon:6.77 liver/hepato:- lung:- bladder:- kidney:6.42 pituitary:7.07 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001109986
Gene ID 29467
Unigene ID Rn.11183
Probe set ID U30186_at  [RG_U34A]
Ensembl ID ENSRNOG00000006789

Orthologous Gene

Human[2]  NM_001195053, NM_001195054, NM_001195055, NM_001195056, NM_001195057, NM_004083
Mouse[1]  NM_007837, NM_001195054, NM_001195055, NM_001195056, NM_001195057, NM_004083

Chromosomal Region

7q22  [67,247,749  -  67,252,571]

Gene Family (Interpro ID)

IPR011700  Basic leucine zipper
IPR004827  Basic-leucine zipper (bZIP) transcription factor

Link to Pubmed  (Pubmed ID)

70575
1283316
8051100
8657121
10419986
10967130
11158311
11691921
11811998
12477932
12609979
12907753
15277470
15476864
15694370
15826945
15829559
15921666
16400006
16936110
17105900
17113167
17395747
17715997
17911345
18006442
19175159
19215662
19218986
19299913
19424493
19614958
19769458
19890920
20026213
20109102
21068199
21225541
21479580
21767604
22083547
22180248
22653339
22705154
22815481
23074209
23239445
23301071
23555658
24133119

Gene Ontology  (GO ID)

Biological Process

GO:0007568  aging
GO:0006915  apoptosis
GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0001955  blood vessel maturation
GO:0007050  cell cycle arrest
GO:0045454  cell redox homeostasis
GO:0048568  embryonic organ development
GO:0030968  endoplasmic reticulum unfolded protein response
GO:0006983  ER overload response
GO:0042789  mRNA transcription from RNA polymerase II promoter
GO:0032792  negative regulation of CREB transcription factor activity
GO:0045662  negative regulation of myoblast differentiation
GO:0043433  negative regulation of transcription factor activity
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0043065  positive regulation of apoptosis
GO:0032757  positive regulation of interleukin-8 production
GO:0043525  positive regulation of neuron apoptosis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0006355  regulation of transcription, DNA-dependent
GO:0051209  release of sequestered calcium ion into cytosol
GO:0001975  response to amphetamine
GO:0042493  response to drug
GO:0034976  response to endoplasmic reticulum stress
GO:0042542  response to hydrogen peroxide
GO:0007584  response to nutrient
GO:0006979  response to oxidative stress
GO:0006950  response to stress
GO:0006986  response to unfolded protein
GO:0006351  transcription, DNA-dependent
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005770  late endosome
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding