glutamate receptor, ionotropic, kainate 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.10 cerebellum:4.07 brain stem:3.92 corpus callosum/glia:- pineal gland:- peripheral nerve:3.51 spine:- retina:- eye:3.82 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:3.69 thymus:3.63 bone marrow:3.75 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:3.81 muscle:3.72 esophagus:- stomach:- intestine:3.65 colon:3.55 liver/hepato:- lung:- bladder:- kidney:3.77 pituitary:3.68 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001111117
Gene ID 29559
Unigene ID Rn.104496
Probe set ID M83561_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000001575

Orthologous Gene

Human[3]  NM_000830, NM_175611
Mouse[2]  NM_010348, NM_146072

Chromosomal Region

11q11  [27,703,875  -  28,106,265]

Gene Family (Interpro ID)

IPR001828  Extracellular ligand-binding receptor
IPR000337  GPCR, family 3
IPR001320  Ionotropic glutamate receptor
IPR001508  NMDA receptor

Link to Pubmed  (Pubmed ID)

1322826
1373382
1977421
8889548
9069287
9259378
10516295
10580501
10627597
11702055
12359272
12533604
12724156
12904467
15458844
15537878
15844209
16360275
16540562
17062563
17395219
17569736
18046310
18678878
19043593
19123252
20848775
22279215

Gene Ontology  (GO ID)

Biological Process

GO:0030534  adult behavior
GO:0048266  behavioral response to pain
GO:0035235  ionotropic glutamate receptor signaling pathway
GO:0051899  membrane depolarization
GO:0032229  negative regulation of synaptic transmission, GABAergic
GO:0051967  negative regulation of synaptic transmission, glutamatergic
GO:0007399  nervous system development
GO:0014054  positive regulation of gamma-aminobutyric acid secretion
GO:0032230  positive regulation of synaptic transmission, GABAergic
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0060080  regulation of inhibitory postsynaptic membrane potential
GO:0042391  regulation of membrane potential
GO:0048172  regulation of short-term neuronal synaptic plasticity
GO:0048167  regulation of synaptic plasticity
GO:0007268  synaptic transmission
GO:0035249  synaptic transmission, glutamatergic

Cellular Component

GO:0030054  cell junction
GO:0043025  cell soma
GO:0030425  dendrite
GO:0008328  ionotropic glutamate receptor complex
GO:0032983  kainate selective glutamate receptor complex
GO:0016020  membrane
GO:0045211  postsynaptic membrane
GO:0042734  presynaptic membrane
GO:0043235  receptor complex
GO:0043195  terminal button

Molecular Function

GO:0008144  drug binding
GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0016595  glutamate binding
GO:0004970  ionotropic glutamate receptor activity
GO:0015277  kainate selective glutamate receptor activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0022843  voltage-gated cation channel activity