glutamate receptor, ionotrophic, AMPA 3

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Synonym

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Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:107.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.83 cerebellum:6.62 brain stem:6.18 corpus callosum/glia:- pineal gland:- peripheral nerve:6.81 spine:- retina:- eye:5.92 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.74 thymus:5.86 bone marrow:5.84 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:114.10 testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:289.90     liver/hepato:-        lung:-    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6.03 muscle:5.91 esophagus:- stomach:- intestine:5.52 colon:5.43 liver/hepato:- lung:- bladder:- kidney:5.88 pituitary:6.12 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001112742
Gene ID 29628
Unigene ID Rn.74049
Probe set ID M36420_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000007682

Orthologous Gene

Human[4]  NM_000828, NM_007325
Mouse[1]  NM_016886, NM_007325

Chromosomal Region

Xq11  [3,452,533  -  3,718,486]

Gene Family (Interpro ID)

IPR001828  Extracellular ligand-binding receptor
IPR001638  Extracellular solute-binding protein, family 3
IPR001320  Ionotropic glutamate receptor
IPR001508  NMDA receptor

Link to Pubmed  (Pubmed ID)

1699275
1699567
2166337
2168579
7992055
8889548
9069286
9647694
9697854
10027300
10340301
10414981
10688364
11348590
11834304
11836517
11891216
12077196
12470884
12477932
12511956
12665613
14706873
14969735
15260958
15269270
15610164
15844209
16436610
17207780
17256974
17873364
18817736
19020286
19200070
19265014
19591855
20869354
21141507
22044924
22871113
23212166
23296627
23375774
23884930

Gene Ontology  (GO ID)

Biological Process

GO:0035235  ionotropic glutamate receptor signaling pathway
GO:0001919  regulation of receptor recycling
GO:0010226  response to lithium ion

Cellular Component

GO:0032281  alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0032279  asymmetric synapse
GO:0030054  cell junction
GO:0043025  cell soma
GO:0030425  dendrite
GO:0043198  dendritic shaft
GO:0043197  dendritic spine
GO:0016021  integral to membrane
GO:0008328  ionotropic glutamate receptor complex
GO:0016020  membrane
GO:0043204  perikaryon
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0043234  protein complex
GO:0043083  synaptic cleft
GO:0043195  terminal button

Molecular Function

GO:0004971  alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0004970  ionotropic glutamate receptor activity
GO:0030165  PDZ domain binding
GO:0005515  protein binding