glutamate receptor, ionotropic, AMPA4

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.91 cerebellum:6.93 brain stem:5.98 corpus callosum/glia:- pineal gland:- peripheral nerve:5.51 spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.29 thymus:5.33 bone marrow:5.49 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:82.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5 muscle:5.67 esophagus:- stomach:- intestine:5.31 colon:5.20 liver/hepato:- lung:- bladder:- kidney:5.33 pituitary:4.87 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001113184
Gene ID 29629
Unigene ID Rn.10938
Probe set ID S94371_g_at  [RG_U34A]
Ensembl ID ENSRNOG00000006957

Orthologous Gene

Human[4]  NM_000829, NM_001077243, NM_001077244, NM_001112812
Mouse[6]  NM_001113180, NM_001113181, NM_019691, NM_001112812

Chromosomal Region

8q11  [956,326  -  1,438,314]

Gene Family (Interpro ID)

IPR001828  Extracellular ligand-binding receptor
IPR001638  Extracellular solute-binding protein, family 3
IPR001320  Ionotropic glutamate receptor
IPR001508  NMDA receptor

Link to Pubmed  (Pubmed ID)

1309749
1372042
1699275
2166337
7992055
8889548
10027300
10688364
11036266
11836517
11891216
11931740
12471040
12473122
12477932
12497607
12911624
14706873
15844209
16246117
17873364
18765917
18817736
19052206
19102704
19200070
19234459
19265014
19439609
19591855
20131911
23296627
23375774

Gene Ontology  (GO ID)

Biological Process

GO:0035235  ionotropic glutamate receptor signaling pathway
GO:0051968  positive regulation of synaptic transmission, glutamatergic
GO:0050803  regulation of synapse structure and activity
GO:0050804  regulation of synaptic transmission
GO:0007268  synaptic transmission

Cellular Component

GO:0032281  alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0030054  cell junction
GO:0043025  cell soma
GO:0030425  dendrite
GO:0016021  integral to membrane
GO:0008328  ionotropic glutamate receptor complex
GO:0032983  kainate selective glutamate receptor complex
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0045202  synapse
GO:0043195  terminal button

Molecular Function

GO:0004971  alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0004970  ionotropic glutamate receptor activity
GO:0015277  kainate selective glutamate receptor activity
GO:0005515  protein binding