ADAM metallopeptidase domain 10

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:319.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:104.70 colon:-     liver/hepato:-        lung:101.30    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001054737
Gene ID 29650
Unigene ID Rn.42924
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

8q24  [75,201,060  -  75,261,382]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8694785
10423016
12354787
12736250
14733940
15688065
15950787
17761886
19455579
20501653
20621845
21145125
21503882
22328515
22489706
24103556

Gene Ontology  (GO ID)

Biological Process

GO:0051089  constitutive protein ectodomain proteolysis
GO:0001701  in utero embryonic development
GO:0006509  membrane protein ectodomain proteolysis
GO:0042117  monocyte activation
GO:0007162  negative regulation of cell adhesion
GO:0007219  Notch signaling pathway
GO:0051088  PMA-inducible membrane protein ectodomain proteolysis
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0010820  positive regulation of T cell chemotaxis
GO:0006468  protein amino acid phosphorylation
GO:0045670  regulation of osteoclast differentiation
GO:0034612  response to tumor necrosis factor

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005794  Golgi apparatus
GO:0005798  Golgi-associated vesicle
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005634  nucleus
GO:0014069  postsynaptic density
GO:0005802  trans-Golgi network

Molecular Function

GO:0004175  endopeptidase activity
GO:0046872  metal ion binding
GO:0004222  metalloendopeptidase activity
GO:0008237  metallopeptidase activity
GO:0042803  protein homodimerization activity
GO:0019901  protein kinase binding
GO:0017124  SH3 domain binding
GO:0008270  zinc ion binding