inhibitor of growth family, member 4

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:143.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:234 thymus:245.80 bone marrow:- adipose:- bone:78.10 skin:-
GeneChip cerebrum:7.98 cerebellum:8.45 brain stem:8.25 corpus callosum/glia:- pineal gland:- peripheral nerve:8.47 spine:- retina:- eye:7.63 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.93 thymus:8.70 bone marrow:7.90 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:1139 placenta:238.90 prostate:38 ovary:114.10 testis:- heart:96.90 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:26.60        lung:202.60    bladder:- kidney:191.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.90 muscle:7.82 esophagus:- stomach:- intestine:7.64 colon:8.04 liver/hepato:- lung:- bladder:- kidney:7.90 pituitary:8.01 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001079887
Gene ID 297597
Unigene ID Rn.48967
Probe set ID rc_AA892937_at  [RG_U34A]
Ensembl ID ENSRNOG00000023363

Orthologous Gene

Human[11]  NM_001127582, NM_001127583, NM_001127584, NM_001127585, NM_001127586, NM_016162
Mouse[2]  NM_133345, NM_001127583, NM_001127584, NM_001127585, NM_001127586, NM_016162

Chromosomal Region

4q42  [161,161,044  -  161,169,602]

Gene Family (Interpro ID)

IPR011011  Zinc finger, FYVE/PHD-type
IPR019787  Zinc finger, PHD-finger
IPR001965  Zinc finger, PHD-type
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

12477932
17517644

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007050  cell cycle arrest
GO:0006978  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260  DNA replication
GO:0043966  histone H3 acetylation
GO:0043983  histone H4-K12 acetylation
GO:0043984  histone H4-K16 acetylation
GO:0043981  histone H4-K5 acetylation
GO:0043982  histone H4-K8 acetylation
GO:0008285  negative regulation of cell proliferation
GO:0045926  negative regulation of growth
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0043065  positive regulation of apoptosis
GO:0006473  protein amino acid acetylation

Cellular Component

GO:0000123  histone acetyltransferase complex
GO:0005634  nucleus

Molecular Function

GO:0035064  methylated histone residue binding
GO:0003713  transcription coactivator activity
GO:0008270  zinc ion binding