telomeric repeat binding factor (NIMA-interacting) 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:245.80 bone marrow:- adipose:- bone:195.20 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:38 ovary:- testis:82.30 heart:38.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:170.70 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001012464
Gene ID 297758
Unigene ID Rn.33853
Probe set ID -
Ensembl ID ENSRNOG00000007291

Orthologous Gene

Human[3]  NM_003218, NM_017489
Mouse[2]  NM_009352, NM_017489

Chromosomal Region

5q11  [2,556,918  -  2,586,086]

Gene Family (Interpro ID)

IPR009057  Homeodomain-like
IPR012287  Homeodomain-related
IPR014778  Myb, DNA-binding
IPR017877  MYB-like
IPR001005  SANT, DNA-binding

Link to Pubmed  (Pubmed ID)

12477932
18720522
19679647
19801496
20127252

Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0001309  age-dependent telomere shortening
GO:0000086  G2/M transition of mitotic cell cycle
GO:0006917  induction of apoptosis
GO:0007094  mitotic cell cycle spindle assembly checkpoint
GO:0008156  negative regulation of DNA replication
GO:0051974  negative regulation of telomerase activity
GO:0032211  negative regulation of telomere maintenance via telomerase
GO:0031116  positive regulation of microtubule polymerization
GO:0045840  positive regulation of mitosis
GO:0045931  positive regulation of mitotic cell cycle
GO:0051260  protein homooligomerization
GO:0042493  response to drug
GO:0007004  telomere maintenance via telomerase
GO:0010834  telomere maintenance via telomere shortening

Cellular Component

GO:0000781  chromosome, telomeric region
GO:0000784  nuclear chromosome, telomeric region
GO:0000783  nuclear telomere cap complex
GO:0005634  nucleus
GO:0005819  spindle

Molecular Function

GO:0008656  caspase activator activity
GO:0003682  chromatin binding
GO:0008301  DNA bending activity
GO:0003691  double-stranded telomeric DNA binding
GO:0008017  microtubule binding
GO:0003674  molecular_function
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0010521  telomerase inhibitor activity
GO:0042162  telomeric DNA binding