dihydrolipoamide dehydrogenase

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:215.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:553.10 spine:- retina:- eye:142.20 artery/aorta:714.30 vein:- lymphnode:- peripheral blood:- spleen:78 thymus:122.90 bone marrow:- adipose:588.80 bone:78.10 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:113.90 ovary:114.10 testis:164.70 heart:329.60 muscle:797.20 esophagus:- stomach:- intestine:209.30 colon:-     liver/hepato:66.50        lung:253.30    bladder:- kidney:191.40 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_199385
Gene ID 298942
Unigene ID Rn.86962
Probe set ID -
Ensembl ID ENSRNOG00000006364

Orthologous Gene

Human[1]  NM_000108
Mouse[2]  NM_007861

Chromosomal Region

6q16  [49,185,189  -  49,205,894]

Gene Family (Interpro ID)

IPR006258  Dihydrolipoamide dehydrogenase
IPR013027  FAD-dependent pyridine nucleotide-disulphide oxidoreductase
IPR016156  FAD/NAD-linked reductase, dimerisation
IPR002218  Glucose-inhibited division protein A-related
IPR000815  Mercuric reductase
IPR000103  Pyridine nucleotide-disulphide oxidoreductase, class-II
IPR004099  Pyridine nucleotide-disulphide oxidoreductase, dimerisation

Link to Pubmed  (Pubmed ID)

3571202
3753688
7487891
8981046
10672230
11795479
12477932
15009635
15489334
18316113
18661235
20645850

Gene Ontology  (GO ID)

Biological Process

GO:0006103  2-oxoglutarate metabolic process
GO:0006086  acetyl-CoA biosynthetic process from pyruvate
GO:0007568  aging
GO:0045454  cell redox homeostasis
GO:0051068  dihydrolipoamide metabolic process
GO:0007369  gastrulation
GO:0009106  lipoate metabolic process
GO:0006120  mitochondrial electron transport, NADH to ubiquinone
GO:0006508  proteolysis
GO:0042391  regulation of membrane potential
GO:0048240  sperm capacitation

Cellular Component

GO:0043159  acrosomal matrix
GO:0005929  cilium
GO:0005759  mitochondrial matrix
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0045252  oxoglutarate dehydrogenase complex
GO:0045254  pyruvate dehydrogenase complex

Molecular Function

GO:0004148  dihydrolipoyl dehydrogenase activity
GO:0050660  FAD binding
GO:0043544  lipoamide binding
GO:0051287  NAD or NADH binding