CCR4-NOT transcription complex, subunit 7

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:95.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:221.20 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:75.90 ovary:114.10 testis:82.30 heart:58.20 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:101.30    bladder:- kidney:63.80 pituitary:177.70 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001107313
Gene ID 306492
Unigene ID Rn.101873
Probe set ID -
Ensembl ID ENSRNOG00000012263

Orthologous Gene

Human[4]  NM_013354, NM_054026
Mouse[3]  NM_011135, NM_054026

Chromosomal Region

16q12.1  [55,118,260  -  55,137,733]

Gene Family (Interpro ID)

IPR012337  Polynucleotidyl transferase, ribonuclease H fold
IPR006941  Ribonuclease CAF1

Link to Pubmed  (Pubmed ID)

9820826
12477932

Gene Ontology  (GO ID)

Biological Process

GO:0033962  cytoplasmic mRNA processing body assembly
GO:0000290  deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0043928  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0031047  gene silencing by RNA
GO:0008285  negative regulation of cell proliferation
GO:0000289  nuclear-transcribed mRNA poly(A) tail shortening
GO:0008284  positive regulation of cell proliferation
GO:0060213  positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0045944  positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0030014  CCR4-NOT complex
GO:0005737  cytoplasm
GO:0000932  cytoplasmic mRNA processing body
GO:0005634  nucleus

Molecular Function

GO:0000175  3'-5'-exoribonuclease activity
GO:0004532  exoribonuclease activity
GO:0003676  nucleic acid binding
GO:0004535  poly(A)-specific ribonuclease activity
GO:0005515  protein binding