coagulation factor XII (Hageman factor)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:452.10        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001014006
Gene ID 306761
Unigene ID Rn.53943
Probe set ID -
Ensembl ID ENSRNOG00000015139

Orthologous Gene

Human[1]  NM_000505
Mouse[1]  NM_021489

Chromosomal Region

17p14  [15,251,611  -  15,259,583]

Gene Family (Interpro ID)

IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3
IPR000001  Kringle
IPR013806  Kringle-like fold
IPR001254  Peptidase S1/S6, chymotrypsin/Hap
IPR001314  Peptidase S1A, chymotrypsin
IPR009003  Serine/cysteine peptidase, trypsin-like
IPR000562  Type II fibronectin, collagen-binding

Link to Pubmed  (Pubmed ID)

2510163
3521732
7974333
10048754
12477932
16046705
16177542
16638441
22216926

Gene Ontology  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0002542  Factor XII activation
GO:0042730  fibrinolysis
GO:0008152  metabolic process
GO:0002353  plasma kallikrein-kinin cascade
GO:0030194  positive regulation of blood coagulation
GO:0051919  positive regulation of fibrinolysis
GO:0010756  positive regulation of plasminogen activation
GO:0016540  protein autoprocessing
GO:0016485  protein processing
GO:0006508  proteolysis
GO:0030193  regulation of blood coagulation
GO:0051788  response to misfolded protein
GO:0031638  zymogen activation

Cellular Component

GO:0005615  extracellular space

Molecular Function

GO:0008233  peptidase activity
GO:0070009  serine-type aminopeptidase activity
GO:0004252  serine-type endopeptidase activity