colony stimulating factor 1 receptor

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:312 thymus:122.90 bone marrow:- adipose:147.20 bone:117.10 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:955.80 prostate:75.90 ovary:114.10 testis:- heart:58.20 muscle:531.50 esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:202.60    bladder:- kidney:63.80 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001029901
Gene ID 307403
Unigene ID Rn.72599
Probe set ID -
Ensembl ID ENSRNOG00000018414

Orthologous Gene

Human[1]  NM_005211
Mouse[3]  NM_001037859

Chromosomal Region

18q12.1  [57,080,324  -  57,107,295]

Gene Family (Interpro ID)

IPR013106  Immunoglobulin V-set
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR020685  Tyrosine-protein kinase
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR016243  Tyrosine-protein kinase, CSF-1/PDGF receptor
IPR020933  Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain
IPR009134  Tyrosine-protein kinase, vascular endothelial growth factor receptor (VEGFR), N-terminal

Link to Pubmed  (Pubmed ID)

1389227
8641359
12381783
12477932
14734466
16170366
16951369
17121910
18510570
18565574
18592004
18987110
19242505
19466391
20536329
22052465
23143303

Gene Ontology  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0045217  cell-cell junction maintenance
GO:0071345  cellular response to cytokine stimulus
GO:0019221  cytokine-mediated signaling pathway
GO:0030097  hemopoiesis
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0030316  osteoclast differentiation
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0046488  phosphatidylinositol metabolic process
GO:0048015  phosphoinositide-mediated signaling
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0090197  positive regulation of chemokine secretion
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0045672  positive regulation of osteoclast differentiation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0046777  protein amino acid autophosphorylation
GO:0045124  regulation of bone resorption
GO:0008360  regulation of cell shape
GO:0031529  ruffle organization
GO:0007519  skeletal muscle tissue development
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0005575  cellular_component
GO:0016021  integral to membrane
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0005524  ATP binding
GO:0019955  cytokine binding
GO:0005011  macrophage colony stimulating factor receptor activity
GO:0003674  molecular_function
GO:0042803  protein homodimerization activity
GO:0019903  protein phosphatase binding