dual specificity phosphatase 19

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:78.10 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:96.90 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001107739
Gene ID 311151
Unigene ID Rn.65563
Probe set ID -
Ensembl ID ENSRNOG00000008868

Orthologous Gene

Human[2]  NM_001142314, NM_080876
Mouse[2]  NM_024438, NM_080876

Chromosomal Region

3q24  [63,473,333  -  63,485,843]

Gene Family (Interpro ID)

IPR000340  Dual specificity phosphatase, catalytic domain
IPR020422  Dual specificity phosphatase, subgroup, catalytic domain
IPR008343  MAP kinase phosphatase

Link to Pubmed  (Pubmed ID)

11959862

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process
GO:0000188  inactivation of MAPK activity
GO:0007254  JNK cascade
GO:0046329  negative regulation of JNK cascade
GO:0043508  negative regulation of JUN kinase activity
GO:0006469  negative regulation of protein kinase activity
GO:0046330  positive regulation of JNK cascade
GO:0043507  positive regulation of JUN kinase activity
GO:0043410  positive regulation of MAPKKK cascade
GO:0045860  positive regulation of protein kinase activity
GO:0006470  protein amino acid dephosphorylation

Cellular Component

GO:0005575  cellular_component
GO:0005737  cytoplasm

Molecular Function

GO:0008579  JUN kinase phosphatase activity
GO:0005078  MAP-kinase scaffold activity
GO:0031434  mitogen-activated protein kinase kinase binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0003674  molecular_function
GO:0030295  protein kinase activator activity
GO:0004860  protein kinase inhibitor activity
GO:0008138  protein tyrosine/serine/threonine phosphatase activity
GO:0008330  protein tyrosine/threonine phosphatase activity