serine/threonine kinase 4

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:71.10 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:122.90 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:228.20 testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:26.60        lung:50.70    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:113.80 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001107800
Gene ID 311622
Unigene ID Rn.166761
Probe set ID -
Ensembl ID ENSRNOG00000013529

Orthologous Gene

Human[2]  NM_006282
Mouse[1]  NM_021420

Chromosomal Region

3q42  [155,014,941  -  155,095,272]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

12477932
23485012

Gene Ontology  (GO ID)

Biological Process

GO:0060706  cell differentiation involved in embryonic placenta development
GO:0000902  cell morphogenesis
GO:0007417  central nervous system development
GO:0003157  endocardium development
GO:0006917  induction of apoptosis
GO:0030216  keratinocyte differentiation
GO:0008285  negative regulation of cell proliferation
GO:0046621  negative regulation of organ growth
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0001841  neural tube formation
GO:0001569  patterning of blood vessels
GO:0018105  peptidyl-serine phosphorylation
GO:0043065  positive regulation of apoptosis
GO:0060215  primitive hemopoiesis
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0007243  protein kinase cascade

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0042802  identical protein binding
GO:0000287  magnesium ion binding
GO:0046983  protein dimerization activity
GO:0042803  protein homodimerization activity
GO:0043539  protein serine/threonine kinase activator activity
GO:0004674  protein serine/threonine kinase activity
GO:0008134  transcription factor binding