enhancer of zeste homolog 2 (Drosophila)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:107.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:110.60 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:- bone marrow:- adipose:- bone:195.20 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:53.20        lung:101.30    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001134979
Gene ID 312299
Unigene ID Rn.9027
Probe set ID -
Ensembl ID ENSRNOG00000006048

Orthologous Gene

Human[2]  NM_001203247, NM_001203248, NM_001203249, NM_004456, NM_152998
Mouse[2]  NM_001146689, NM_007971, NM_001203249, NM_004456, NM_152998

Chromosomal Region

4q24  [75,709,959  -  75,773,279]

Gene Family (Interpro ID)

IPR009057  Homeodomain-like
IPR012287  Homeodomain-related
IPR001005  SANT, DNA-binding

Link to Pubmed  (Pubmed ID)

12477932
22194015
22222375
22821416
22873822
23727574
23932971

Gene Ontology  (GO ID)

Biological Process

GO:0021695  cerebellar cortex development
GO:0070314  G1 to G0 transition
GO:0070734  histone H3-K27 methylation
GO:0016571  histone methylation
GO:0045605  negative regulation of epidermal cell differentiation
GO:0010629  negative regulation of gene expression
GO:0045814  negative regulation of gene expression, epigenetic
GO:0048387  negative regulation of retinoic acid receptor signaling pathway
GO:0034244  negative regulation of RNA elongation from RNA polymerase II promoter
GO:0051154  negative regulation of striated muscle cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0043406  positive regulation of MAP kinase activity
GO:0032320  positive regulation of Ras GTPase activity
GO:0042127  regulation of cell proliferation
GO:0010468  regulation of gene expression
GO:0014013  regulation of gliogenesis
GO:0050767  regulation of neurogenesis
GO:0001932  regulation of protein amino acid phosphorylation

Cellular Component

GO:0005737  cytoplasm
GO:0035098  ESC/E(Z) complex
GO:0005634  nucleus
GO:0045120  pronucleus

Molecular Function

GO:0003682  chromatin binding
GO:0042054  histone methyltransferase activity
GO:0018024  histone-lysine N-methyltransferase activity
GO:0003723  RNA binding
GO:0043565  sequence-specific DNA binding