membrane-associated ring finger (C3HC4) 8

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:122.90 bone marrow:- adipose:147.20 bone:39 skin:-
GeneChip cerebrum:5.90 cerebellum:5.81 brain stem:6.07 corpus callosum/glia:- pineal gland:- peripheral nerve:5.68 spine:- retina:- eye:6.23 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.81 thymus:4.91 bone marrow:7.18 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:189.80 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:209.30 colon:-     liver/hepato:53.20        lung:101.30    bladder:- kidney:- pituitary:296.10 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5.48 muscle:5.65 esophagus:- stomach:- intestine:6.51 colon:6.83 liver/hepato:- lung:- bladder:- kidney:6.29 pituitary:6.88 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001107882
Gene ID 312656
Unigene ID Rn.48069
Probe set ID rc_AI231778_at  [RG_U34A]
Ensembl ID ENSRNOG00000012297

Orthologous Gene

Human[3]  NM_001002265, NM_001002266, NM_145021
Mouse[1]  NM_027920, NM_001002266, NM_145021

Chromosomal Region

4q42  [152,494,801  -  152,609,538]

Gene Family (Interpro ID)

IPR018957  Zinc finger, C3HC4 RING-type
IPR011016  Zinc finger, RING-CH-type
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0002495  antigen processing and presentation of peptide antigen via MHC class II
GO:0045347  negative regulation of MHC class II biosynthetic process
GO:0000209  protein polyubiquitination
GO:0016567  protein ubiquitination

Cellular Component

GO:0005768  endosome
GO:0005764  lysosome

Molecular Function

GO:0042289  MHC class II protein binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding