SRY (sex determining region Y)-box 17

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.39 cerebellum:4.97 brain stem:5.15 corpus callosum/glia:- pineal gland:- peripheral nerve:5.84 spine:- retina:- eye:5.31 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.31 thymus:5.29 bone marrow:5.34 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:238.90 prostate:- ovary:114.10 testis:- heart:58.20 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:152    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:227.60 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5.53 muscle:5.62 esophagus:- stomach:- intestine:5.31 colon:5.30 liver/hepato:- lung:- bladder:- kidney:5.34 pituitary:5.58 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001107902
Gene ID 312936
Unigene ID Rn.7884
Probe set ID rc_AA799800_at  [RG_U34A]
Ensembl ID ENSRNOG00000027357

Orthologous Gene

Human[1]  NM_022454
Mouse[2]  NM_011441

Chromosomal Region

5q12  [15,241,405  -  15,246,904]

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR000910  High mobility group, HMG1/HMG2
IPR000135  High mobility group, HMG1/HMG2, subgroup
IPR009071  High mobility group, superfamily
IPR002062  Oxytocin receptor
IPR001817  Vasopressin receptor

Link to Pubmed  (Pubmed ID)

12477932
20816680

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0008150  biological_process
GO:0060913  cardiac cell fate determination
GO:0003142  cardiogenic plate morphogenesis
GO:0042074  cell migration involved in gastrulation
GO:0048617  embryonic foregut morphogenesis
GO:0035050  embryonic heart tube development
GO:0003143  embryonic heart tube morphogenesis
GO:0048568  embryonic organ development
GO:0060956  endocardial cell differentiation
GO:0060214  endocardium formation
GO:0007492  endoderm development
GO:0001706  endoderm formation
GO:0007493  endodermal cell fate determination
GO:0007369  gastrulation
GO:0001947  heart looping
GO:0001828  inner cell mass cellular morphogenesis
GO:0042789  mRNA transcription from RNA polymerase II promoter
GO:0030308  negative regulation of cell growth
GO:0042662  negative regulation of mesodermal cell fate specification
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0003308  negative regulation of Wnt receptor signaling pathway involved in heart development
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0003151  outflow tract morphogenesis
GO:0045597  positive regulation of cell differentiation
GO:0010628  positive regulation of gene expression
GO:0045732  positive regulation of protein catabolic process
GO:0048643  positive regulation of skeletal muscle tissue development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0031648  protein destabilization
GO:0050821  protein stabilization
GO:0045595  regulation of cell differentiation
GO:0045995  regulation of embryonic development
GO:0042661  regulation of mesodermal cell fate specification
GO:0060807  regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification
GO:0006355  regulation of transcription, DNA-dependent
GO:0021903  rostrocaudal neural tube patterning
GO:0007283  spermatogenesis
GO:0048863  stem cell differentiation
GO:0048866  stem cell fate specification
GO:0001570  vasculogenesis
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005575  cellular_component
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0008013  beta-catenin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003674  molecular_function
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003713  transcription coactivator activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding