ribosomal protein S6 kinase, polypeptide 5

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:227.60 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001108048
Gene ID 314384
Unigene ID Rn.8940
Probe set ID -
Ensembl ID ENSRNOG00000004362

Orthologous Gene

Human[3]  NM_004755, NM_182398
Mouse[2]  NM_153587, NM_182398

Chromosomal Region

6q32  [124,820,623  -  124,999,790]

Gene Family (Interpro ID)

IPR000961  AGC-kinase, C-terminal
IPR017892  Protein kinase, C-terminal
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

11994045
15893597
16421520
16531007
21493629
22004609
22082260
23065332

Gene Ontology  (GO ID)

Biological Process

GO:0043990  histone H2A-S1 phosphorylation
GO:0043987  histone H3-S10 phosphorylation
GO:0043988  histone H3-S28 phosphorylation
GO:0016572  histone phosphorylation
GO:0070498  interleukin-1-mediated signaling pathway
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0035066  positive regulation of histone acetylation
GO:0033129  positive regulation of histone phosphorylation
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0007243  protein kinase cascade
GO:0006355  regulation of transcription, DNA-dependent
GO:0009605  response to external stimulus
GO:0006950  response to stress

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0005840  ribosome

Molecular Function

GO:0005524  ATP binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity