CASP2 and RIPK1 domain containing adaptor with death domain

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:38 ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001108085
Gene ID 314756
Unigene ID Rn.162947
Probe set ID -
Ensembl ID ENSRNOG00000008507

Orthologous Gene

Human[2]  NM_003805
Mouse[2]  NM_009950

Chromosomal Region

7q13  [32,504,279  -  32,517,581]

Gene Family (Interpro ID)

IPR001315  Caspase Recruitment
IPR011029  DEATH-like

Link to Pubmed  (Pubmed ID)

14765136

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0071260  cellular response to mechanical stimulus
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0006917  induction of apoptosis

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0070513  death domain binding
GO:0002020  protease binding
GO:0030674  protein binding, bridging