promyelocytic leukemia

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001074703
Gene ID 315713
Unigene ID Rn.214058
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

8q24  [62,020,450  -  62,049,433]

Gene Family (Interpro ID)

IPR000315  Zinc finger, B-box
IPR018957  Zinc finger, C3HC4 RING-type
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

15833741
22082260

Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0008150  biological_process
GO:0060444  branching involved in mammary gland duct morphogenesis
GO:0007569  cell aging
GO:0007050  cell cycle arrest
GO:0045165  cell fate commitment
GO:0071353  cellular response to interleukin-4
GO:0007182  common-partner SMAD protein phosphorylation
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0032469  endoplasmic reticulum calcium ion homeostasis
GO:0006917  induction of apoptosis
GO:0008631  induction of apoptosis by oxidative stress
GO:0051457  maintenance of protein location in nucleus
GO:0030099  myeloid cell differentiation
GO:0016525  negative regulation of angiogenesis
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0045930  negative regulation of mitotic cell cycle
GO:0051974  negative regulation of telomerase activity
GO:0032211  negative regulation of telomere maintenance via telomerase
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0032938  negative regulation of translation in response to oxidative stress
GO:0030578  PML body organization
GO:0060058  positive regulation of apoptosis involved in mammary gland involution
GO:0002230  positive regulation of defense response to virus by host
GO:0031065  positive regulation of histone deacetylation
GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0006461  protein complex assembly
GO:0050821  protein stabilization
GO:0006605  protein targeting
GO:0010522  regulation of calcium ion transport into cytosol
GO:0045343  regulation of MHC class I biosynthetic process
GO:0001932  regulation of protein amino acid phosphorylation
GO:0006355  regulation of transcription, DNA-dependent
GO:0034097  response to cytokine stimulus
GO:0010332  response to gamma radiation
GO:0001666  response to hypoxia
GO:0009411  response to UV
GO:0048384  retinoic acid receptor signaling pathway
GO:0007184  SMAD protein nuclear translocation
GO:0007179  transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0005575  cellular_component
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0042406  extrinsic to endoplasmic reticulum membrane
GO:0005622  intracellular
GO:0016363  nuclear matrix
GO:0031965  nuclear membrane
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0016605  PML body

Molecular Function

GO:0050897  cobalt ion binding
GO:0003674  molecular_function
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0046332  SMAD binding
GO:0032183  SUMO binding
GO:0003713  transcription coactivator activity
GO:0031625  ubiquitin protein ligase binding
GO:0008270  zinc ion binding