solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:38 ovary:- testis:82.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001031658
Gene ID 316519
Unigene ID Rn.105919
Probe set ID -
Ensembl ID ENSRNOG00000014956

Orthologous Gene

Human[4]  NM_000578
Mouse[1]  NM_013612

Chromosomal Region

9q33  [73,714,692  -  73,725,509]

Gene Family (Interpro ID)

IPR001046  Natural resistance-associated macrophage protein

Link to Pubmed  (Pubmed ID)

8875897
9461570
10608779
10719815
10857800
11791966
11821237
11929588
12135431
12429222
12477932
12847242
14734525
14960532
15118671
15489334
15584484
15755200
15757519
15877293
16059695
16516037
16550170
16734634
17035062
17067929
17122779
17131479
17385031
17876529
18340647
18454481
18656410
18973068
18998137
19016783
19116231
19768110
19863441
20089160
21128323
21169917
21233146
21524304
22160516

Gene Ontology  (GO ID)

Biological Process

GO:0032147  activation of protein kinase activity
GO:0048002  antigen processing and presentation of peptide antigen
GO:0008150  biological_process
GO:0070574  cadmium ion transmembrane transport
GO:0006876  cellular cadmium ion homeostasis
GO:0006879  cellular iron ion homeostasis
GO:0042742  defense response to bacterium
GO:0050829  defense response to Gram-negative bacterium
GO:0042832  defense response to protozoan
GO:0070839  divalent metal ion export
GO:0006954  inflammatory response
GO:0032623  interleukin-2 production
GO:0032632  interleukin-3 production
GO:0006811  ion transport
GO:0055072  iron ion homeostasis
GO:0006826  iron ion transport
GO:0043091  L-arginine import
GO:0042116  macrophage activation
GO:0071421  manganese ion transmembrane transport
GO:0006828  manganese ion transport
GO:0045342  MHC class II biosynthetic process
GO:0048255  mRNA stabilization
GO:0060586  multicellular organismal iron ion homeostasis
GO:0001818  negative regulation of cytokine production
GO:0015707  nitrite transport
GO:0006909  phagocytosis
GO:0001819  positive regulation of cytokine production
GO:0002606  positive regulation of dendritic cell antigen processing and presentation
GO:0010628  positive regulation of gene expression
GO:0032729  positive regulation of interferon-gamma production
GO:0050766  positive regulation of phagocytosis
GO:0002827  positive regulation of T-helper 1 type immune response
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0000060  protein import into nucleus, translocation
GO:0045730  respiratory burst
GO:0009617  response to bacterium
GO:0034341  response to interferon-gamma
GO:0032496  response to lipopolysaccharide
GO:0002369  T cell cytokine production
GO:0002309  T cell proliferation during immune response
GO:0007035  vacuolar acidification
GO:0042060  wound healing

Cellular Component

GO:0009279  cell outer membrane
GO:0009986  cell surface
GO:0005575  cellular_component
GO:0010008  endosome membrane
GO:0016021  integral to membrane
GO:0005770  late endosome
GO:0005764  lysosome
GO:0030670  phagocytic vesicle membrane
GO:0005886  plasma membrane
GO:0070821  tertiary granule membrane

Molecular Function

GO:0005384  manganese ion transmembrane transporter activity
GO:0051139  metal ion:hydrogen antiporter activity
GO:0003674  molecular_function
GO:0042803  protein homodimerization activity
GO:0046915  transition metal ion transmembrane transporter activity
GO:0005215  transporter activity