DnaJ (Hsp40) homolog, subfamily A, member 3

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:75.90 ovary:- testis:82.30 heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:101.30    bladder:- kidney:191.40 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001038595
Gene ID 360481
Unigene ID Rn.198254
Probe set ID -
Ensembl ID ENSRNOG00000003855

Orthologous Gene

Human[2]  NM_001135110, NM_005147
Mouse[4]  NM_001135112, NM_023646

Chromosomal Region

10q12  [10,984,721  -  11,009,374]

Gene Family (Interpro ID)

IPR003095  Heat shock protein DnaJ
IPR015609  Molecular chaperone, heat shock protein, Hsp40, DnaJ

Link to Pubmed  (Pubmed ID)

15030183
22016808

Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0006924  activation-induced cell death of T cells
GO:0006915  apoptosis
GO:0007569  cell aging
GO:0008219  cell death
GO:0009790  embryonic development
GO:0006264  mitochondrial DNA replication
GO:0007005  mitochondrion organization
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0008285  negative regulation of cell proliferation
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0060336  negative regulation of interferon-gamma-mediated signaling pathway
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0006469  negative regulation of protein kinase activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007528  neuromuscular junction development
GO:0043065  positive regulation of apoptosis
GO:0031398  positive regulation of protein ubiquitination
GO:0042102  positive regulation of T cell proliferation
GO:0006457  protein folding
GO:0050821  protein stabilization
GO:0050790  regulation of catalytic activity
GO:0009408  response to heat
GO:0034341  response to interferon-gamma
GO:0071340  skeletal muscle nicotinic acetylcholine receptor clustering
GO:0007264  small GTPase mediated signal transduction
GO:0033077  T cell differentiation in the thymus

Cellular Component

GO:0005884  actin filament
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0019897  extrinsic to plasma membrane
GO:0033256  I-kappaB/NF-kappaB complex
GO:0008385  IkappaB kinase complex
GO:0005759  mitochondrial matrix
GO:0042645  mitochondrial nucleoid
GO:0005739  mitochondrion
GO:0031594  neuromuscular junction
GO:0005634  nucleus
GO:0045211  postsynaptic membrane

Molecular Function

GO:0005524  ATP binding
GO:0030544  Hsp70 protein binding
GO:0005133  interferon-gamma receptor binding
GO:0046872  metal ion binding
GO:0051059  NF-kappaB binding
GO:0019901  protein kinase binding
GO:0030971  receptor tyrosine kinase binding
GO:0005083  small GTPase regulator activity
GO:0008134  transcription factor binding
GO:0051082  unfolded protein binding