NLR family, pyrin domain containing 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:147.20 bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:289.90     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001145755
Gene ID 360557
Unigene ID Rn.12490
Probe set ID -
Ensembl ID ENSRNOG00000023143

Orthologous Gene

Human[10]  NM_001033053, NM_014922, NM_033004, NM_033006
Mouse[3]  NM_001004142, NM_001040696, NM_001162414, NM_033006

Chromosomal Region

10q24  [57,963,708  -  58,007,898]

Gene Family (Interpro ID)

IPR003593  ATPase, AAA+ type, core
IPR001315  Caspase Recruitment
IPR011029  DEATH-like

Link to Pubmed  (Pubmed ID)

18068672
19401709
19416975
20303873
20502689
22133203
22479187

Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0008219  cell death
GO:0006952  defense response
GO:0042742  defense response to bacterium
GO:0051402  neuron apoptosis
GO:0050718  positive regulation of interleukin-1 beta secretion
GO:0042981  regulation of apoptosis
GO:0032495  response to muramyl dipeptide

Cellular Component

GO:0043025  cell soma
GO:0005622  intracellular
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0005524  ATP binding
GO:0019899  enzyme binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding