T-box 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:213.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001108322
Gene ID 360737
Unigene ID Rn.41347
Probe set ID -
Ensembl ID ENSRNOG00000001892

Orthologous Gene

Human[5]  NM_005992, NM_080646, NM_080647
Mouse[1]  NM_011532, NM_080646, NM_080647

Chromosomal Region

11q23  [84,400,980  -  84,410,631]

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR003980  Histamine H3 receptor
IPR008967  p53-like transcription factor, DNA-binding
IPR002070  Transcription factor, Brachyury
IPR001699  Transcription factor, T-box

Link to Pubmed  (Pubmed ID)

15469978
15703190
16141220

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0009952  anterior/posterior pattern formation
GO:0048844  artery morphogenesis
GO:0008150  biological_process
GO:0001568  blood vessel development
GO:0048514  blood vessel morphogenesis
GO:0001974  blood vessel remodeling
GO:0001708  cell fate specification
GO:0008283  cell proliferation
GO:0071300  cellular response to retinoic acid
GO:0090103  cochlea morphogenesis
GO:0060982  coronary artery morphogenesis
GO:0007368  determination of left/right symmetry
GO:0042471  ear morphogenesis
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0048703  embryonic viscerocranium morphogenesis
GO:0070166  enamel mineralization
GO:0030855  epithelial cell differentiation
GO:0060325  face morphogenesis
GO:0007507  heart development
GO:0003007  heart morphogenesis
GO:0042472  inner ear morphogenesis
GO:0001945  lymph vessel development
GO:0007498  mesoderm development
GO:0042474  middle ear morphogenesis
GO:0042693  muscle cell fate commitment
GO:0007517  muscle organ development
GO:0048644  muscle organ morphogenesis
GO:0060415  muscle tissue morphogenesis
GO:0045596  negative regulation of cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0001755  neural crest cell migration
GO:0042475  odontogenesis of dentine-containing tooth
GO:0042473  outer ear morphogenesis
GO:0003151  outflow tract morphogenesis
GO:0003148  outflow tract septum morphogenesis
GO:0060017  parathyroid gland development
GO:0007389  pattern specification process
GO:0060037  pharyngeal system development
GO:0008284  positive regulation of cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0043410  positive regulation of MAPKKK cascade
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0050793  regulation of developmental process
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0048384  retinoic acid receptor signaling pathway
GO:0048752  semicircular canal morphogenesis
GO:0007605  sensory perception of sound
GO:0035176  social behavior
GO:0060023  soft palate development
GO:0048538  thymus development
GO:0030878  thyroid gland development
GO:0043587  tongue morphogenesis
GO:0006351  transcription, DNA-dependent
GO:0021644  vagus nerve morphogenesis

Cellular Component

GO:0005575  cellular_component
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0003674  molecular_function
GO:0042803  protein homodimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity