alkB, alkylation repair homolog 3 (E. coli)

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:110.60 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:245.80 bone marrow:- adipose:- bone:195.20 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:- ovary:228.20 testis:329.40 heart:232.70 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:50.70    bladder:- kidney:63.80 pituitary:177.70 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001014180
Gene ID 362169
Unigene ID Rn.30490
Probe set ID -
Ensembl ID ENSRNOG00000021678

Orthologous Gene

Human[1]  NM_139178
Mouse[1]  NM_026944

Chromosomal Region

3q24  [78,386,101  -  78,418,432]

Gene Family (Interpro ID)

IPR005123  Oxoglutarate/iron-dependent oxygenase

Link to Pubmed  (Pubmed ID)

12477932
15489334

Gene Ontology  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0006307  DNA dealkylation
GO:0080111  DNA demethylation
GO:0006281  DNA repair
GO:0055114  oxidation reduction

Cellular Component

GO:0005737  cytoplasm
GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0051747  DNA demethylase activity
GO:0043734  DNA-N1-methyladenine dioxygenase activity
GO:0004519  endonuclease activity
GO:0004527  exonuclease activity
GO:0008198  ferrous iron binding
GO:0016706  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen