spastin

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:71.10 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:114.10 testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:104.70 colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:191.40 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001108702
Gene ID 362700
Unigene ID Rn.41645
Probe set ID -
Ensembl ID ENSRNOG00000027136

Orthologous Gene

Human[4]  NM_014946, NM_199436
Mouse[4]  NM_001162870, NM_016962

Chromosomal Region

6q12  [20,992,743  -  21,048,866]

Gene Family (Interpro ID)

IPR003593  ATPase, AAA+ type, core
IPR003959  ATPase, AAA-type, core

Link to Pubmed  (Pubmed ID)

11723204
12477932

Gene Ontology  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0007109  cytokinesis, completion of separation
GO:0006888  ER to Golgi vesicle-mediated transport
GO:0001578  microtubule bundle formation
GO:0051013  microtubule severing
GO:0031117  positive regulation of microtubule depolymerization
GO:0034214  protein hexamerization
GO:0051260  protein homooligomerization

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005783  endoplasmic reticulum
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0005874  microtubule
GO:0015630  microtubule cytoskeleton
GO:0030496  midbody
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005819  spindle

Molecular Function

GO:0043014  alpha-tubulin binding
GO:0005524  ATP binding
GO:0048487  beta-tubulin binding
GO:0008017  microtubule binding
GO:0008568  microtubule-severing ATPase activity