CCR4-NOT transcription complex, subunit 8

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:119.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:110.60 spine:- retina:- eye:142.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:234 thymus:491.60 bone marrow:- adipose:441.60 bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:1139 placenta:119.50 prostate:38 ovary:- testis:- heart:77.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:253.30    bladder:- kidney:127.60 pituitary:236.90 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001008382
Gene ID 363603
Unigene ID Rn.203142
Probe set ID -
Ensembl ID ENSRNOG00000002630

Orthologous Gene

Human[3]  NM_004779
Mouse[2]  NM_026949

Chromosomal Region

10q22  [43,743,277  -  43,751,851]

Gene Family (Interpro ID)

IPR012337  Polynucleotidyl transferase, ribonuclease H fold
IPR006941  Ribonuclease CAF1

Link to Pubmed  (Pubmed ID)

12477932

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process
GO:0043928  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0008284  positive regulation of cell proliferation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0030014  CCR4-NOT complex
GO:0005575  cellular_component
GO:0005622  intracellular
GO:0005634  nucleus

Molecular Function

GO:0000175  3'-5'-exoribonuclease activity
GO:0003674  molecular_function
GO:0003676  nucleic acid binding
GO:0004535  poly(A)-specific ribonuclease activity