cardiotrophin-like cytokine factor 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_207615
Gene ID 365395
Unigene ID Rn.130193
Probe set ID -
Ensembl ID ENSRNOG00000018752

Orthologous Gene

Human[2]  NM_001166212, NM_013246
Mouse[3]  NM_019952, NM_013246

Chromosomal Region

1q42  [206,802,745  -  206,806,328]

Gene Family (Interpro ID)

IPR009079  Four-helical cytokine-like, core
IPR010681  Plethodontid receptivity factor PRF

Link to Pubmed  (Pubmed ID)

12090754
12477932
15034937

Gene Ontology  (GO ID)

Biological Process

GO:0030183  B cell differentiation
GO:0007166  cell surface receptor linked signal transduction
GO:0007259  JAK-STAT cascade
GO:0043524  negative regulation of neuron apoptosis
GO:0048711  positive regulation of astrocyte differentiation
GO:0030890  positive regulation of B cell proliferation
GO:0008284  positive regulation of cell proliferation
GO:0002639  positive regulation of immunoglobulin production
GO:0048295  positive regulation of isotype switching to IgE isotypes
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein

Cellular Component

GO:0005576  extracellular region

Molecular Function

GO:0005127  ciliary neurotrophic factor receptor binding
GO:0005125  cytokine activity
GO:0046982  protein heterodimerization activity
GO:0005102  receptor binding