E2F transcription factor 1

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:78.10 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:75.90 ovary:- testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001065036
Gene ID 399489
Unigene ID Rn.72471
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

3q41  [145,032,489  -  145,043,729]

Gene Family (Interpro ID)

IPR003316  Transcription factor E2F/dimerisation partner (TDP)
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

3951992
8653789
8653790
8673024
9697699
12063292
14514686
15124020
15146237
15158336
15990448
16717102
17102628
17147820
17404573
17482685
17555552
17989570
18096822
18348166
18364697
18367454
18541936
18768156
18818403
19088195
19180667
20299467
21614651
21641965
21937878
21964190
22592528
22848730
24453336

Gene Ontology  (GO ID)

Biological Process

GO:0043276  anoikis
GO:0006915  apoptosis
GO:0071398  cellular response to fatty acid
GO:0071363  cellular response to growth factor stimulus
GO:0071456  cellular response to hypoxia
GO:0000077  DNA damage checkpoint
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0030900  forebrain development
GO:0000082  G1/S transition of mitotic cell cycle
GO:0048255  mRNA stabilization
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0048146  positive regulation of fibroblast proliferation
GO:0010628  positive regulation of gene expression
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051726  regulation of cell cycle
GO:0006355  regulation of transcription, DNA-dependent
GO:0007283  spermatogenesis
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0035189  Rb-E2F complex
GO:0005667  transcription factor complex

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding