bone morphogenetic protein 10

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001031824
Gene ID 500245
Unigene ID Rn.118010
Probe set ID -
Ensembl ID ENSRNOG00000009316

Orthologous Gene

Human[1]  NM_014482
Mouse[1]  NM_009756

Chromosomal Region

4q34  [121,596,150  -  121,601,778]

Gene Family (Interpro ID)

IPR002405  Inhibin, alpha subunit
IPR001111  Transforming growth factor beta (TGFb), N-terminal
IPR016319  Transforming growth factor-beta
IPR015615  Transforming growth factor-beta-related

Link to Pubmed  (Pubmed ID)

15978772
17921333
22797972

Gene Ontology  (GO ID)

Biological Process

GO:0032924  activin receptor signaling pathway
GO:0007512  adult heart development
GO:0055009  atrial cardiac muscle tissue morphogenesis
GO:0030509  BMP signaling pathway
GO:0060038  cardiac muscle cell proliferation
GO:0007507  heart development
GO:0060347  heart trabecula formation
GO:0010614  negative regulation of cardiac muscle hypertrophy
GO:0030308  negative regulation of cell growth
GO:0030336  negative regulation of cell migration
GO:0010596  negative regulation of endothelial cell migration
GO:0060389  pathway-restricted SMAD protein phosphorylation
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0010613  positive regulation of cardiac muscle hypertrophy
GO:0010628  positive regulation of gene expression
GO:0010862  positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0060298  positive regulation of sarcomere organization
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0055117  regulation of cardiac muscle contraction
GO:0045214  sarcomere organization
GO:0055015  ventricular cardiac muscle cell development
GO:0055010  ventricular cardiac muscle tissue morphogenesis

Cellular Component

GO:0009986  cell surface
GO:0005575  cellular_component
GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0030018  Z disc

Molecular Function

GO:0005125  cytokine activity
GO:0008083  growth factor activity
GO:0005179  hormone activity
GO:0003674  molecular_function
GO:0033612  receptor serine/threonine kinase binding